Jozef Vanden Broeck
This research group is investigating the physiological role and biochemical/biophysical mode of action of neural and endocrine messenger molecules in developmental processes of insects. These processes are studied in an evolutionary context by comparative approaches. Our major aim is to unravel the cellular and organismal physiological mechanisms implicated in the regulation of important post-embryonic developmental processes, such as growth and reproduction, as well as the remarkable phase polyphenism that can be observed in locust species. In particular, we are specialized in the study of receptors for neuropeptides and biogenic amines and their signal transduction pathways in insect cells. We are also investigating the mechanisms of systemic RNA interference in insects. In addition, application-oriented research is carried out to explore novel strategies for pest control and to efficiently convert organic waste products into biomass via insects (e.g. Chitinsect, Insects4Food).
- Badisco L., Ott S., Rogers S., Matheson T., Knapen D., Vergauwen L., Verlinden H., Marchal E., Sheehy M., Burrows M., Vanden Broeck J. 2011. Microarray-based transcriptomic analysis of differences between long-term gregarious and solitarious desert locusts. PLoS One. vol.6 (11) , pp. 1-8
- Ott S., Verlinden H., Rogers S., Brighton C., Quah P., Vleugels R., Verdonck R., Vanden Broeck J. 2012. Critical role for PKA in the acquisition of gregarious behaviour in the Desert Locust. Proceedings of the National Academy of Sciences of the United States of America. vol.109 (7) , pp. E381-E387
- Marchal E., Zhang J., Badisco L., Verlinden H., Hult E., Van Wielendaele P., Yagi K., Tobe S., Vanden Broeck J. 2011. Final steps in juvenile hormone biosynthesis in the desert locust, Schistocerca gregaria. Insect Biochemistry and Molecular Biology. vol.41 (4) , pp. 219-227
- Poels J., Van Loy T., Vandersmissen H., Van Hiel B., Van Soest S., Nachman R., Vanden Broeck J. 2010. Myoinhibiting peptides are the ancestral ligands of the promiscuous Drosophila sex peptide receptor. Cellular and Molecular Life Sciences. vol.67 (20) , pp. 3511-3522