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Lut Arckens

Lut Arckens
Naamsestraat 59 - box 2467
3000 Leuven
Belgium
room: 02.08

tel: +32 16 32 39 51 or +32163 30283
fax: +32163 23902

Our central research goal is to unravel the influence of loss of retinal input on the connectivity/structure and function of the mammalian visual cortex in different visual impairment models (enucleation, hooding, glaucoma). Our research critically challenges the contribution of a uni- and multimodal component to sensory cortex plasticity. Understanding different aspects of cortical plasticity will facilitate the development of treatments for visual disorders that target the eye-brain axis. Our strategy encompasses molecular, cellular and systems approaches using state of the art technology including functional proteomics, tract tracing and molecular/cellular activity mapping in mouse, rat and cat. The lab develops and refines methods relevant to neurobiology research, like optogenetics, which allows manipulating the activity of specific neuronal or glial subtypes. With cortical plasticity being central to learning and memory my lab also invests in implementing this expertise in collaborative research on complex learning.

Selected publications