Our main research interest concerns the mechanisms of brain plasticity in health, disease and ageing. Our stratified approach targets the molecular, cellular and systems level. We develop and apply state-of-the-art technologies, including neuronal activity mapping, tract tracing, drug/toxin administration, optogenetics, pharmacogenetics, functional proteomics and cell sorting strategies to disentangle cell type-specific and cell circuit contributions. We maximize our efforts by comparing species with different capacities for neuroplasticity including killifish, mouse and cat. Our long-term objective is to create knowledge and understanding of new cellular mediators and central molecular and structural mechanisms of brain plasticity to boost the development of novel pharmaceuticals and therapies to compensate for CNS damage.

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Research Group of Neuroplasticity and Neuroproteomics
Naamsestraat 59 BOX 2467
B-3000 Leuven

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