Rubio-Texeira M., Van Zeebroeck G. and Thevelein J.M.

Peptides induce persistent signaling from endosomes by a nutrient transceptor.

Nature Chemical Biology [In Press]

Tournu H. and Van Dijck P.

Candida biofilms and the host: models and new concepts for eradication.

International Journal of Microbiology [In Press]  [ pubmed ]

Castermans D., Somers I., Kriel J., Louwet W., Wera S., Versele M., Janssens V. and Thevelein J.M.

Glucose-induced post-translational activation of protein phosphatases PP2A and PP1 in yeast.

Cell Research [In Press]

Swinnen S., Thevelein J.M. and Nevoigt E.

Genetic mapping of quantitative phenotypic traits in Saccharomyces cerevisiae.

FEMS Yeast Research [In press]  [ pubmed ]

Lackman P., González-Guzmán M., Tilleman S., Carqueijeiro I., Pérez A.C., Moses T., Seo M., Kanno Y., Häkkinen ST., Van Montagu MC., Thevelein J.M., Maaheimo H., Oksman-Caldentey K.M., Rodriguez P.L., Rischer H. and Goossens A.

Jasmonate signaling involves the abscisic acid receptor PYL4 to regulate metabolic reprogramming in Arabidopsis and tobacco.

Proceedings of the National Academy of Sciences (USA) 108, 5891-5896  [ pubmed ]

Kriel J., Haesendonckx S., Rubio-Texeira M., Van Zeebroeck G. and Thevelein J.M.

From transporter to transceptor: signaling from transporters provokes re-evaluation of complex trafficking and regulatory controls.

BioEssays 33, 870-879  [ pubmed ]

Van Zeebroeck G., Kimpe M., Vandormael P. and Thevelein J.M.

A split-ubiquitin two-hybrid system screen for proteins physically interacting with the yeast amino acid transceptor Gap1 and ammonium transceptor Mep2.

PLoS ONE 6: e24275  [ pubmed ]

Kraidlova L., Van Zeebroeck G., Van Dijck P. and Sychrova H.

The Candida albicans GAP Gene Family Encodes Permeases Involved in General and Specific Amino-Acid Uptake and Sensing.

Eukaryot Cell 10, 1219-1229  [ pubmed ]

Hubmann G., Guillouet S. and Nevoigt E.

Gpd1 and Gpd2 fine tuning for sustainable reduction of glycerol formation in Saccharomyces cerevisiae.

Applied and Environmental Microbiology 77, 5857-5867  [ pubmed ]

Henry I.M., Carpentier S.C., Pampurova S., Van Hoylandt A., Panis B., Swennen R. and Remy S.

Structure and regulation of the Asr gene family in banana.

Planta 234, 785-798  [ pubmed ]

Voordeckers K., Kimpe M., Haesendonckx S., Louwet W., Versele M. and Thevelein JM.

Yeast 3-Phosphoinositide-dependent protein kinase-1 (PDK1) orthologs, Pkh1-3, differentially regulate phosphorylation of PKA and the PKB/S6K ortholog, Sch9.

Journal of Biological Chemistry 286, 22017-22027  [ pubmed ]

Verhaert P.D., Pinkse M.W., Strupat K. and Conaway M.C.

Imaging of similar mass neuropeptides in neuronal tissue by enhanced resolution MALDI MS with an ion trap - Orbitrap hybrid instrument.

Methods in Molecular Biology 656, 433-449  [ pubmed ]

Vianna C.R., Ferreira M.C., Silva C.L., Tanghe A., Neves M.J., Thevelein J.M., Rosa C.A. and Van Dijck P.

Stress tolerance of the Saccharomyces cerevisiae adenylate cyclase fil1 (CYR1^lys1682) mutant depends on Hsp26.

Journal of Molecular Microbiology and Biotechnology 19, 140-146  [ pubmed ]

Saerens S.M., Delvaux F.R., Verstrepen K.J. and Thevelein J.M.

Production and biological function of volatile esters in Saccharomyces cerevisiae

Microbial Biotechnology 4, 32-46  [ pubmed ]

Stynen B., Van Dijck P. and Tournu H.

A CUG codon adapted two-hybrid system for the pathogenic fungus Candida albicans.

Nucleic Acids Research 38, e184  [ pubmed ]

Kucharikovi S., Tournu H., Holtappels M., Van Dijck P. and Lagrou K.

In vivo Efficacy of anidulafungin against Candida albicans mature biofilms in a novel rat model of catheter-associated candidiasis.

Antimicrobial Agents and Chemotherapy 54, 4474-4475  [ pubmed ]

Wilson D., Fiori A., De Brucker K., Van Dijck P. and Stateva L.

Candida albicans Pdelp and Gpa2p comprise a regulatory module mediating agonist-induced cAMP signalling and environmental adaptation.

Fungal Genetics and Biology 47, 742-752  [ pubmed ]

Nailis H., Kucharíková S., Ricicová M., Van Dijck P., Deforce D., Nelis H. and Coenye T.

Real-time PCR expression profiling of genes encoding potential virulence factors in Candida albicans biofilms: identification of model-dependent and -independent gene expression.

BMC Microbiology 10, 114  [ pubmed ]

Vandesteene L., Ramon M., Le Roy K., Van Dijck P. and Rolland F.

A Single Active Trehalose-6-P Synthase (TPS) and a Family of Putative Regulatory TPS-Like Proteins in Arabidopsis.

Molecular Plant 3, 406-419  [ pubmed ]

Popova Y., Thayumanavan P., Lonati E., Agrochão M. and Thevelein J.M.

Transport and signaling through the phosphate-binding site of the yeast Pho84 phosphate transceptor.

Proceedings of the National Academy of Sciences (USA) 107, 2890-2895  [ pubmed ]

Rubio-Texeira M., Van Zeebroeck G., Voordeckers K. and Thevelein J.M.

Saccharomyces cerevisiae plasma membrane nutrient sensors and their role in PKA signaling.

FEMS Yeast Research 10, 134-149  [ pubmed ]

de Melo H.F., Bonini B.M., Thevelein J., Simões D.A. and Morais M.A. Jr.

Physiological and molecular analysis of the stress response of Saccharomyces cerevisiae imposed by strong inorganic acid with implication to industrial fermentations.

Journal of Applied Microbiology 109, 116-127  [ pubmed ]

Ricicova M., Kucharikova S., Tournu H., Hendrix J., Bujdakova H., Van Eldere J., Lagrou K. and Van Dijck P.

Candida albicans biofilm formaton in a new in vivo rat model.

Microbiology 156(Pt.3), 909-919  [ pubmed ]

Avonce N., Wuyts J., Verschooten K., Vandesteene L. and Van Dijck P.

The Cytophaga hutchinsonii ChTPSP: first characterized bifunctional TPS-TPP protein as putative ancestor of all eukaryotic trehalose biosynthesis proteins.

Molecular Biology and Evolution 27, 359-369  [ pubmed ]

Van Dijck P.

Nutrient sensing G protein-coupled receptors: interesting targets for antifungals?

Medical Mycology 47, 671-680  [ pubmed ]

Thevelein J.M. and Voordeckers K.

Functioning and evolutionary significance of nutrient transceptors.

Molecular Biology and Evolution 26, 2407-2414  [ pubmed ]

Anthonio E.A., Brees C., Baumgart-Vogt E., Hongu T., Huybrechts S.J., Van Dijck P., Mannaerts G.P., Kanaho Y., Van Veldhoven P.P. and Fransen M.

Small G proteins in peroxisome biogenesis: the potential involvement of ADP-ribosylation factor 6.

BMC Cell Biology 10, 58  [ pubmed ]

Lundh F., Mouillon J.M., Samyn D., Stadler K., Popova Y., Lagerstedt J.O., Thevelein J.M. and Persson B.L.

Molecular mechanisms controlling phosphate-induced downregulation of the yeast Pho84 phosphate transporter.

Biochemistry 48, 4497-4505  [ pubmed ]

Noubhani A., Bunoust O., Bonini B.M., Thevelein J.M., Devin A. and Rigoulet M.

The trehalose pathway regulates mitochondrial respiratory chain content through hexokinase 2 and cAMP in Saccharomyces cerevisiae.

Journal of Biological Chemistry 284, 27229-27234  [ pubmed ]

Ramon M., De Smet I., Vandesteene L., Naudts M., Leyman B., Van Dijck P., Rolland F., Beeckman T. and Thevelein J.M.

Extensive expression regulation and lack of heterologous enzymatic activity of the Class II trehalose metabolism proteins from Arabidopsis thaliana.

Plant, Cell & Environment 8, 1015-1032  [ pubmed ]

Storkebaum E., Leitão-Gonçalves R., Godenschwege T., Nangle L., Mejia M., Bosmans I., Ooms T., Jacobs A., Van Dijck P., Yang X.L., Schimmel P., Norga K., Timmerman V., Callaerts P. and Jordanova A.

Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human Charcot-Marie-Tooth neuropathy.

Proceedings of the National academy of Sciences of the United States of America 106, 11782-11787  [ pubmed ]

Van Zeebroeck G., Bonini B.M., Versele M. and Thevelein J.M.

Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Nature Chemical Biology 5, 45-52  [ pubmed ]

Verbelen P.J., Dekoninck T.M., Saerens S.M., Van Mulders S.E., Thevelein J.M. and Delvaux F.R.

Impact of pitching rate on yeast fermentation performance and beer flavour.

Applied Microbiology and Biotechnology 82, 155-167  [ pubmed ]

Saerens S.M., Verbelen P.J., Vanbeneden N., Thevelein J.M. and Delvaux F.R.

Monitoring the influence of high-gravity brewing and fermentation temperature on flavour formation by analysis of gene expression levels in brewing yeast.

Applied Microbiology and Biotechnology 80, 1039-1051  [ pubmed ]

Zvyagilskaya R.A., Lundh F., Samyn D., Pattison-Granberg J., Mouillon J.M., Popova Y., Thevelein J.M. and Persson B.L.

Characterization of the Pho89 phosphate transporter by functional hyperexpression in Saccharomyces cerevisiae.

FEMS Yeast Research 8, 685-696  [ pubmed ]

Nazarko V.Y., Futej K.O., Thevelein J.M. and Sibirny A.A.

Differences in glucose sensing and signaling for pexophagy between the baker's yeast Saccharomyces cerevisiae and the methylotrophic yeast Pichia pastoris.

Autophagy 4, 381-384  [ pubmed ]

Nazarko V.Y., Thevelein J.M. and Sibirny A.A.

G-protein-coupled receptor Gpr1 and G-protein Gpa2 of cAMP-dependent signaling pathway are involved in glucose-induced pexophagy in the yeast Saccharomyces cerevisiae.

Cell Biology International 32, 502-504  [ pubmed ]

Thevelein J.M., Bonini B.M., Castermans D., Haesendonckx S., Kriel J., Louwet W., Thayumanavan P., Popova Y., Rubio-Texeira M., Schepers W., Vandormael P., Van Zeebroeck G., Verhaert P., Versele M. and Voordeckers K.

Novel mechanisms in nutrient activation of the yeast protein kinase A pathway.

Acta microbiologica et immunologica Hungarica 55, 75-89  [ pubmed ]

Maere S., Van Dijck P. and Kuiper M.

Extracting expression modules from perturbational gene expression compendia.

BMC Systems Biology 2, 33  [ pubmed ]

Stasyk O.G., Maidan M.M., Stasyk O.V., Van Dijck P., Thevelein J.M. and Sibirny A.A.

Identification of hexose transporter-like sensor Hxs1 and functional hexose transporter Hxt1 in the methylotrophic yeast Hansenula polymorpha.

Eukaryotic Cell 7, 735-746  [ pubmed ]

Van Laere S.D., Saerens S.M., Verstrepen K.J., Van Dijck P., Thevelein J.M. and Delvaux F.R.

Flavour formation in fungi: characterisation of KlAtf, the Kluyveromyces lactis orthologue of the Saccharomyces cerevisiae alcohol acetyltransferases Atf1 and Atf2.

Applied Microbiology and Biotechnology 78, 783-792  [ pubmed ]

Maidan M.M., De Rop L., Relloso M., Diez-Orejas R., Thevelein J.M. and Van Dijck P.

Combined inactivation of the Candida albicans GPR1 and TPS2 genes results in a-virulence in a mouse model for systemic infection.

Infection and Immunity 76, 1686-1694  [ pubmed ]

Saerens S.M., Delvaux F., Verstrepen K.J., Van Dijck P., Thevelein J.M. and Delvaux F.R.

Parameters affecting ethyl ester production by Saccharomyces cerevisiae during fermentation.

Applied and Environmental Microbiology 74, 454-461  [ pubmed ]

Berthels N.J., Cordero Otero R.R., Bauer F.F., Pretorius I.S. and Thevelein J.M.

Correlation between glucose/fructose discrepancy and hexokinase kinetic properties in different Saccharomyces cerevisiae wine yeast strains.

Applied Microbiology and Biotechnology 77, 1083-1091  [ pubmed ]

Van de Velde S. and Thevelein J.M.

cAMP-PKA and Snf1 signaling mechanisms underlie the superior potency of sucrose for induction of filamentation in yeast.

Eukaryotic Cell 7, 286-293  [ pubmed ]

Peeters T., Versele M. and Thevelein J.M.

Directly from G to Protein Kinase A: the kelch repeat protein bypass of adenylyl cyclase.

Trends in Biochem Sciences 32, 547-554  [ pubmed ]

Baena-Gonzalez E., Rolland F., Thevelein J.M. and Sheen J.

A central integrator of transcription networks in plant stress and energy signalling.

Nature 448, 938-942  [ pubmed ]

Dietvorst J., Blieck L., Brandt R., Van Dijck P. and Steensma H.Y.

Attachment of MAL32-encoded maltase on the outside of yeast cells improves maltotriose utilization.

Yeast 24, 27-38  [ pubmed ]

Miranda J.A., Avonce N., Suárez R., Thevelein J.M., Van Dijck P. and Iturriaga G.

A bifunctional TPS-TPP enzyme from yeast confers tolerance to multiple and extreme abiotic-stress conditions in transgenic Arabidopsis.

Planta 226, 1411-1421  [ pubmed ]

Biswas S., Van Dijck P. and Datta A.

Environmental sensing and signal transduction pathways regulating morphopathogenic determinants of Candida albicans.

Microbiology and Molecular Biology Reviews 71, 348-376  [ pubmed ]

Blieck L., Toye G., Dumortier F., Verstrepen K.J., Delvaux F.R., Thevelein J.M. and Van Dijck P.

Isolation and characterization of brewer's yeast variants with improved fermentation performance under high-gravity conditions.

Applied and Environmental Microbiology 73, 815-824  [ pubmed ]

Karim S., Aronsson H., Ericson H., Pirhonen M., Leyman B., Welin B., Mantyla E., Palva E.T., Van Dijck P. and Holmstrom KO.

Improved drought tolerance without undesired side effects in transgenic plants producing trehalose.

Plant Molecular Biology 64, 371-386  [ pubmed ]

Ramon M. and Rolland F.

Plant development: introducing trehalose metabolism

Trends in Plant Science 12, 185-188  [ pubmed ]

Almeida A.M., Santos M., Villalobos E., Araujo S.S., Van Dijck P., Leyman B., Cardoso L.A., Santos D., Fevereiro P.S. and Torne J.M.

Immunogold localization of trehalose-6-phosphate synthase in leaf segments of wild-type and transgenic tobacco plants expressing the AtTPS1 gene from Arabidopsis thaliana.

Protoplasma 230, 41-49  [ pubmed ]

Ramon M., Rolland F., Thevelein J.M., Van Dijck P. and Leyman B.

ABI4 mediates the effects of exogenous trehalose on Arabidopsis growth and starch breakdown.

Plant Molecular Biology 63, 195-206  [ pubmed ]

Vastiau I.M.K., Anthonio E.A., Brams M., Brees C., Young S.G., Van de Velde S., Wanders R.J.A., Mannaerts G.P., Baes M., Van Veldhoven P.P. and Fransen M.

Farnesylation of Pex19p is not essential for peroxisome biogenesis in yeast and mammalian cells.

Cellular and Molecular Life Sciences 63, 1686-1699  [ pubmed ]

Peeters T., Louwet W., Gelade R., Nauwelaers D., Thevelein J.M. and Versele M.

Kelch-repeat proteins interacting with the Galpha protein Gpa2 bypass adenylate cyclase for direct regulation of protein kinase A in yeast.

Proceedings of the National Academy of Sciences of the USA 103, 13034-13039  [ pubmed ]

Rolland F., Baena-Gonzalez E. and Sheen J.

Sugar Sensing and Signaling in Plants: Conserved and Novel Mechanisms.

Annual Reviews of Plant Biology 57, 675-709  [ pubmed ]

Walker G. and Van Dijck P.

Physiological and molecular responses of yeast to the environment.

In: 'Yeast Handbook vol 2: Yeasts in Food and Beverages', Editors: Querol A. and Fleet G., Springer Verlag, Heidelberg. pp. 111-152

Soveral G., Veiga A., Loureiro-Dias M.C., Tanghe A., Van Dijck P. and Moura T.F.

Water channels are important for osmotic adjustments of yeast cells at low temperature.

Microbiology 152, 1515-1521  [ pubmed ]

Saerens S.M., Verstrepen K.J., Van Laere S.D., Voet A.R., Van Dijck P., Delvaux F.R. and Thevelein J.M.

The Saccharomyces cerevisiae EHT1 and EEB1 genes encode novel enzymes with medium-chain fatty acid ethyl ester synthesis and hydrolysis capacity.

Journal of Biological Chemistry 281, 4446-4456  [ pubmed ]

Van Nuland A., Vandormael P., Donaton M., Alenquer, A. Louren�o M., Quintino E., Versele M. and Thevelein J.M.

Ammonium permease-based sensing mechanism for rapid ammonium activation of the protein kinase A pathway in yeast.

Molecular Microbiology 59, 1485-1505  [ pubmed ]

Tanghe A., Van Dijck P. and Thevelein J.M.

Why do micro-organisms have aquaporins ?

Trends in Microbiology 14, 78-85  [ pubmed ]

Tanghe A., Prior B. and Thevelein J.M.

Yeast responses to stresses.

In: 'Biodiversity and ecophysiology of yeasts'. Eds. C.A. Rosa and P. Gábor. Springer Verlag, Heidelberg.

Leyman B., Avonce N., Ramon M., Van Dijck P., Iturriaga G. and Thevelein J.M.

Trehalose-6-phosphate synthase as an intrinsic selection marker for plant transformation.

Journal of Biotechnology 121, 309-317  [ pubmed ]

Jordanova A., Irobi J., Thomas F.P., Van Dijck P., Meerschaert K., Dewil M., Jacobs A., De Vriendt E., Van Gerwen V., Guerguelcheva V., Tournev I., Van Den Bosch L., Timmermans J.-P., Robberecht W., Gettemans J., Thevelein J.M., De Jonghe P., Kremensky I. and Timmerman V.

Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase associated with dominant intermediate Charcot-Marie-Tooth neuropathy.

Nature Genetics 38, 197-202  [ pubmed ]

Rolland F. and Sheen J.

Sugar sensing and signaling networks in plants.

Biochemical Society Transactions 33, 269-271  [ pubmed ]

Versele M. and Thorner J.

Some assembly required: yeast septins provide the instruction manual.

Trends in Cell Biology 15, 414-424  [ pubmed ]

Almeida A.M., Villalobos E., Araújo S.S., Leyman B., Van Dijck P., Alfaro-Cardoso L., Fevereiro P.S., Torné J.M. and Santos D.M.

Transformation of tobacco with an Arabidopsis thaliana gene involved in trehalose biosynthesis increases tolerance to several abiotic stresses.

Euphytica 146, 165-176

Tournu H., Serneels J. and Van Dijck P.

Fungal pathogens research: novel and improved molecular approaches for the discovery of antifungal drug targets.

Current Drug Targets 6, 909-922.  [ pubmed ]

Tanghe A., Kayingo G., Prior B.A., Thevelein J.M. and Van Dijck P.

Heterologous aquaporin (AQY2-1) expression strongly enhances freeze tolerance of Schizosaccharomyces pombe.

Journal of Molecular Microbiology and Biotechnology 9, 52-56  [ pubmed ]

Tanghe A., Carbrey J.M., Agre P., Thevelein J.M. and Van Dijck P.

Aquaporin expression and freeze tolerance in Candida albicans.

Applied and Environmental Microbiology 71, 6434-6437  [ pubmed ]

Maidan M.M., De Rop L., Serneels J., Exler S., Rupp S., Tournu H., Thevelein J.M. and Van Dijck P.

The G protein-coupled receptor Gpr1 and the Galpha; protein Gpa2 act through the cAMP-PKA pathway to induce morphogenesis in Candida albicans.

Molecular Biology of the Cell 16, 1971-1986  [ pubmed ]

Roosen J., Engelen K., Marchal K., Mathys J., Griffioen G., Cameroni E., Thevelein J.M., De Virgilio C., De Moor B. and Winderickx J.

PKA and Sch9 control a molecular switch important for the proper adaptation to nutrient availability.

Molecular Microbiology 55, 862-880  [ pubmed ]

Maidan M.M., Thevelein J.M. and Van Dijck P.

Carbon source induced yeast to hypha transition in Candida albicans is dependent on the presence of amino acids and on the G protein-coupled receptor Gpr1.

Biochemical Society Transactions 33, 291-293  [ pubmed ]

Avonce N., Leyman B., Thevelein J. and Iturriaga G.

Trehalose metabolism and glucose sensing in plants.

Biochemical Society Transactions 33, 276-279  [ pubmed ]

Thevelein J.M., Gelade R., Holsbeeks I., Lagatie O., Popova Y., Rolland F., Stolz F., Van de Velde S., Van Dijck P., Vandormael P., Van Nuland A., Van Roey K., Van Zeebroeck G. and Yan B.

Nutrient sensing systems for rapid activation of the protein kinase A pathway in yeast.

Biochemical Society Transactions 33, 253-256  [ pubmed ]

Pakkiri L.S., Wolucka B.A., Lubert E.J. and Waechter C.J.

Structural and topological studies on the lipid-mediated assembly of a membrane-associated lipomannan in Micrococcus luteus.

Glycobiology 14, 73-81  [ pubmed ]

Thevelein J.M.

Conference report 'Nutrient sensing through the plasma membrane of eukaryotic cells, Cirencester, U.K., 25-29 Sept. 2004'

FEMS Yeast Research 5, 303-305

Avonce N., Leyman B., Mascorro-Gallardo J.O., Van Dijck P., Thevelein J.M. and Iturriaga G.

The Arabidopsis trehalose-6-P synthase AtTPS1 gene is a regulator of glucose, abscisic acid, and stress signaling.

Plant Physiology 136, 3649-3659  [ pubmed ]

Colombo S., Ronchetti D., Thevelein J.M., Winderickx J. and Martegani E.

Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae.

Journal of Biological Chemistry 279, 46715-46722  [ pubmed ]

Avonce N., Leyman B., Thevelein J.M. and Iturriaga G.

Trehalose metabolism and glucose sensing in plants.

Biochemical Society Transactions 33, 276-279  [ pubmed ]

Lemaire K., Van de Velde S., Van Dijck P. and Thevelein J.M.

Glucose and sucrose act as agonist and mannose as antagonist ligands of the G-protein coupled receptor Gpr1 in the yeast Saccharomyces cerevisiae.

Molecular Cell 16, 293-297  [ pubmed ]

Holsbeeks I., Lagatie O., Van Nuland A., Van de Velde S. and Thevelein J.M.

The eukaryotic plasma membrane as a nutrient-sensing device.

Trends in Biochemical Sciences 29, 556-564  [ pubmed ]

Verstrepen K.J., Iserentant D., Malcorps P., Derdelinckx G., Van Dijck P., Winderickx J., Pretorius I.S., Thevelein J.M. and Delvaux F.R.

Glucose and sucrose: hazardous fast-food for industrial yeast?

Trends in Biotechnology 22, 531-537  [ pubmed ]

Tanghe A., Van Dijck P., Colavizza D. and Thevelein J.M.

Aquaporin-mediated improvement of freeze tolerance of Saccharomyces cerevisiae is restricted to rapid freezing conditions.

Applied and Environmental Microbiology 70, 3377-3382  [ pubmed ]

Berthels N.J., Cordero Otero R.R., Bauer F.F., Thevelein J.M. and Pretorius I.S.

Discrepancy in glucose and fructose utilisation during fermentation by Saccharomyces cerevisiae wine yeast strains.

FEMS Yeast Research 4, 683-689  [ pubmed ]

Leyman B., Avonce N., Ramon M., Van Dijck P., Thevelein J.M. and Iturriaga G.

New selection marker for plant transformation.

In: 'Recombinant Gene Expression. Reviews and Protocols', 2^nd edition. Editors: Paulina Balbas and Argelia Lorence. Series: Methods in Molecular Biology (J. Walker, ed.) Humana Press, Totowa, N.J., 267, 385-396  [ pubmed ]

Tisi R., Belotti F., Wera S., Winderickx J., Thevelein J.M. and Martegani E.

Evidence for inositol triphosphate as a second messenger for glucose-induced calcium signalling in budding yeast.

Current Genetics 45, 83-89  [ pubmed ]

Versele M., Thevelein J.M. and Van Dijck P.

The high general stress resistance of the Saccharomyces cerevisiae fil1 adenylate cyclase mutant (Cyr1^Lys1682) is only partially dependent on trehalose, Hsp104 and overexpression of Msn2/4 regulated genes.

Yeast 21, 75-86  [ pubmed ]

Verstrepen K.J. and Thevelein J.M.

Controlled expression of homologous genes by genomic promoter replacement in the yeast Saccharomyces cerevisiae.

In: 'Recombinant Gene Expression. Reviews and Protocols', 2^nd edition. Editors: Paulina Balbas and Argelia Lorence. Series: Methods in Molecular Biology (J. Walker, ed.) Humana Press, Totowa, N.J. pp. 259-265  [ pubmed ]

Verstrepen K.J., Van Laere S.D., Vercammen J., Derdelinckx G., Dufour J.P., Pretorius I.S., Winderickx J., Thevelein J.M. and Delvaux F.R.

The Saccharomyces cerevisiae alcohol acetyl transferase Atf1p is localized in lipid particles.

Yeast 21, 367-377  [ pubmed ]

Bonini B.M., Van Dijck P. and Thevelein J.M.

Trehalose metabolism: enzymatic pathways and physiological functions.

In: The Mycota : A Treatise on the Biology of Fungi with Emphasis on Systems for Fundamental and Applied Research. (K. Esser and P.A. Lemke, eds.) Vol. III Biochemistry and Molecular Biology (R. Brambl and G.A. Marzluf, eds.). Second Edition. Springer Verlag, Berlin-Heidelberg. pp. 291-332

Verstrepen K.J., Derdelinckx G., Dufour J.-P., Winderickx J., Pretorius I.S., Thevelein J.M.

The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways.

FEMS Yeast Research 4, 285-296

Gelade R., Vandevelde S., Van Dijck P. and Thevelein J.M.

Multi-level response of the yeast genome to glucose.

Genome Biology 4:233  [ pubmed ]

Donaton M.C.V., Holsbeeks I., Lagatie O., Van Zeebroeck G., Crauwels M., Winderickx J. and Thevelein J.M.

The Gap1 general amino acid permease acts as an amino acid sensor for activation of Protein Kinase A targets in the yeast Saccharomyces cerevisiae.

Molecular Microbiology 50, 911-929  [ pubmed ]

Bonini B.M., Van Dijck P. and Thevelein J.M.

Uncoupling of the glucose growth defect and the deregulation of glycolysis in Saccharomyces cerevisiae tps1 mutants expressing trehalose-6-phosphate insensitive hexokinase from Schizosaccharomyces pombe.

Biochimica et Biophysica Acta Bioenergetics 1606, 83-93  [ pubmed ]

Tanghe A., Van Dijck P. and Thevelein J.M.

Determinants of freeze tolerance in microorganisms, physiological importance and biotechnological applications.

Advances in Applied Microbiology 53, 129-176

Verstrepen K.J., Van Laere S.D.M., Vanderhaegen B.M.P., Derdelinckx G., Dufour J.-P., Pretorius I.S., Winderickx J., Thevelein J.M. and Delvaux F.R.

Expression levels of the yeast alcohol acetyltransferase genes ATF1, Lg-ATF1 and ATF2 control the formation of a broad range of volatile esters.

Applied and Environmental Microbiology 69, 5228-5237  [ pubmed ]

Griffioen G., Swinnen S. and Thevelein J.M.

Feedback inhibition on cell wall integrity signaling by Zds1 involves Gsk3 phosphorylation of a cAMP-dependent protein kinase regulatory subunit.

Journal of Biological Chemistry 278, 23460-23471  [ pubmed ]

Verstrepen K.J., Derdelinckx G., Dufour J-P., Winderickx J., Thevelein J.M., Pretorius I.S. and Delvaux F.R.

Flavour-active esters: adding fruitiness to beer.

Journal of Bioscience and Bioengineering 96, 110-118

Portela P., Van Dijck P., Thevelein J.M. and Moreno S.

Activation state of Protein Kinase A as measured in permeabilised Saccharomyces cerevisiae cells correlates with PKA-controlled phenotypes in vivo.

FEMS Yeast Research 3, 119-126  [ pubmed ]

Verstrepen K.J., Moonjai N., Derdelinckx G., Dufour J.-P., Winderickx J., Thevelein J.M., Pretorius I.S. and Delvaux F.R.

Genetic regulation of ester synthesis in yeast: new facts, insights and implications for the brewer.

In: 'Brewing Yeast Fermentation Performance'. K. Smart (ed.). Blackwell Science Ltd, Oxford, UK. pp. 234-248

Tamas M.J., Karlgren S., Bill R.M., Hedfalk K., Allegri L., Ferreira M., Thevelein J.M., Rydstrom J., Mullins J.G.L. and Hohmann S.

A short regulatory domain restricts glycerol transport through yeast Fps1p.

Journal of Biological Chemistry 278, 6337-6345  [ pubmed ]

Giots F., Donaton M.C.V. and Thevelein J.M.

Inorganic phosphate is sensed by specific phosphate carriers and acts in concert with glucose as a nutrient signal for activation of the protein kinase A pathway in the yeast Saccharomyces cerevisiae.

Molecular Microbiology 47, 1163-1181  [ pubmed ]

Winderickx J., Holsbeeks I., Lagatie O., Giots F., Thevelein J.M. and de Winde H.

From Feast to Famine; Adaptation to nutrient availability in yeast.

In: 'Yeast Stress Responses'. Topics in Current Genetics Vol.1. Hohmann S. and P.W.H. Mager (Eds.) Springer-Verlag, Berlin. Chapter 7; p.305-386

Thevelein J.M.

Conference report 'The XXth International Conference on Yeast Genetics and Molecular Biology, Prague'

FEMS Yeast Research 1, 339-340

Griffioen G. and Thevelein J.M.

Molecular mechanisms controlling the localisation of protein kinase A.

Current Genetics 41, 199-207  [ pubmed ]

Tanghe A., Van Dijck P., Dumortier F., Teunissen A., Hohmann S. and Thevelein J.M.

Aquaporin expression correlates with freeze tolerance in yeast and overexpression improves freeze tolerance in industrial yeast.

Applied and Environmental Microbiology 68, 5981-5989  [ pubmed ]

Teunissen A., Dumortier F., Gorwa M.-F., Bauer J., Tanghe A., Loiez A., Smet P., Van Dijck P. and Thevelein J.M.

Isolation and characterization of a freeze-tolerant diploid derivative of an industrial baker's yeast strain and its use in frozen doughs.

Applied and Environmental Microbiology 68, 4780-4787  [ pubmed ]

Van Dijck P., Mascorro-Gallardo J.O., De Bus M., Royackers K., Iturriaga G. and Thevelein J.M.

Truncation of Arabidopsis thaliana and Selaginella lepidophylla trehalose-6-phosphate synthase unlocks high catalytic activity and supports high trehalose levels on expression in yeast.

Biochemical Journal 366, 63-71  [ pubmed ]

Zabrocki P., Swiatek W., Sugajska E., Thevelein J.M., Wera S. and Zolnierowicz S.

The Saccharomyces cerevisiae type-2A protein phosphatase Pph22 is biochemically different from mammalian PP2A.

European Journal of Biochemistry 269, 3372-3382  [ pubmed ]

Brandao R.L., Etchebehere L., Queiroz C.C., Tropia M.J., Ernandes J.R., Goncalves T., Loureiro-Dias M.C., Winderickx J., Thevelein J.M., Leiper F.C., Carling D. and Castro I.M.

Evidence for involvement of Saccharomyces cerevisiae protein kinase C in glucose induction of HXT genes and derepression of SUC2.

FEMS Yeast Research 2, 93-102  [ pubmed ]

Rolland F., Winderickx J. and Thevelein J.M.

Glucose-sensing and -signalling mechanisms in yeast.

FEMS Yeast Research. Special Thematic Conference Section "Physiology of Yeasts and Filamentous Fungi." 2, 183-201  [ pubmed ]

Van Dijck P., De Rop L., Szlufcik K., Van Ael E. and Thevelein J.M.

Disruption of the Candida albicans TPS2 gene encoding trehalose-6-phosphate phosphatase decreases infectivity without affecting hypha formation.

Infection and Immunity 70, 1772-1782  [ pubmed ]

Zabrocki P., Van Hoof C., Goris J., Thevelein J.M., Winderickx J. and Wera S.

Protein phosphatase 2A on track for nutrient-induced signalling in yeast.

Molecular Microbiology 43, 835-842  [ pubmed ]

Bergsma J.C., Kasri N.N., Donaton M.C., De Wever V., Tisi R., de Winde J.H., Martegani E., Thevelein J.M. and Wera S.

PtdIns(4,5)P(2) and phospholipase C-independent Ins(1,4,5)P(3) signals induced by a nitrogen source in nitrogen-starved yeast cells.

Biochemical Journal 359, 517-523  [ pubmed ]

Verstrepen K.J., Derdelinckx G., Delvaux F.R., Winderickx J., Thevelein J.M., Bauer F.F. and Pretorius I.S.

Late fermentation expression of FLO1 in Saccharomyces cerevisiae.

Journal of the American Society of Brewing Chemists 59, 69-76

Verstrepen K.J., Bauer F.F., Winderickx J., Derdelinckx G., Dufour J.-P., Thevelein J.M., Pretorius I.S. and Delvaux F.R.

Genetic modification of Saccharomyces cerevisiae: fitting the modern brewer's needs.

Cerevisiae 26, 89-97

Versele M. and Thevelein J.M.

Lre1 affects chitinase expression, trehalose accumulation and heat resistance through inhibition of the Cbk1 protein kinase in Saccharomyces cerevisiae.

Molecular Microbiology 41, 1311-1326  [ pubmed ]

Versele M., Lemaire K. and Thevelein J.M.

Sex and sugar in yeast: two distinct GPCR systems.

EMBO Reports 2, 574-579  [ pubmed ]

Brown A.J., Planta R.J., Restuhadi F., Bailey D.A., Butler P.R., Cadahia J.L., Cerdan M.E., De Jonge M., Gardner D.C., Gent M.E., Hayes A., Kolen C.P., Lombardia L.J., Murad A.M., Oliver R.A., Sefton M., Thevelein J.M., Tournu H., van Delft Y.J., Verbart D.J., Winderickx J. and Oliver S.G.

Transcript analysis of 1003 novel yeast genes using high-throughput northern hybridizations.

EMBO Journal 20, 3177-3186  [ pubmed ]

Wysocki R., Chery C.C., Wawrzycka D., Van Hulle M., Cornelis R., Thevelein J.M. and Tamas M.J.

The glycerol channel Fps1p mediates the uptake of arsenite and antimonite in Saccharomyces cerevisiae.

Molecular Microbiology 40, 1391-1401  [ pubmed ]

Rep M., Proft M., Remize F., Tamas M., Serrano R., Thevelein J.M. and Hohmann S.

The Saccharomyces cerevisiae Sko1p transcription factor mediates HOG pathway-dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage.

Molecular Microbiology 40, 1067-1083  [ pubmed ]

Rolland F., Winderickx J. and Thevelein J.M.

Glucose-sensing mechanisms in eukaryotic cells.

Trends in Biochemical Sciences 26, 310-317  [ pubmed ]

Rolland F., Wanke V., Cauwenberg L., Ma P., Boles E., Vanoni M., de Winde J.H., Thevelein J.M. and Winderickx J.

The role of hexose transport and phosphorylation in cAMP signalling in the yeast Saccharomyces cerevisiae.

FEMS Yeast Research 1403, 1-13

Van Hoof C., Janssens V., De Baere I., Stark M.J., de Winde J.H., Winderickx J., Thevelein J.M., Merlevede W. and Goris J.

The Saccharomyces cerevisiae phosphotyrosyl phosphatase activator proteins are required for a subset of the functions disrupted by protein phosphatase 2A mutations.

Experimental Cell Research 264, 372-387  [ pubmed ]

Leyman B., Van Dijck P. and Thevelein J.M.

An unexpected plethora of trehalose biosynthesis genes in Arabidopsis thaliana.

Trends in Plant Science 6, 510-513  [ pubmed ]

Sugajska E., Swiatek W., Zabrocki P., Geyskens I., Thevelein J.M., Zolnierowicz S. and Wera S.

Multiple effects of protein phosphatase 2A on nutrient-induced signalling in the yeast Saccharomyces cerevisiae.

Molecular Microbiology 4, 1020-1026  [ pubmed ]

Wera S., Bergsma J.C.T. and Thevelein J.M.

Phosphoinositides in yeast: genetically tractable signalling.

FEMS Yeast Research 1, 9-13

Geyskens I., Kumara S.H.M.C., Donaton M.C.V., Bergsma J.C.T., Thevelein J.M. and Wera S.

Expression of mammalian PKB partially complements deletion of the yeast protein kinase Sch9.

Nato Science Series A316, 117-126

Fillinger S., Ruijter G., Tamas M.J., Visser J., Thevelein J.M. and d'enfert C.

Molecular and physiological characterization of the NAD-dependent glycerol 3-phosphate dehydrogenase in the filamentous fungus Aspergillus nidulans.

Molecular Microbiology 39, 145-157  [ pubmed ]

van Vaeck C., Wera S., Van Dijck P. and Thevelein J.M.

Analysis and modification of trehalose 6-phosphate levels in the yeast Saccharomyces cerevisiae with the use of Bacillus subtilis phosphotrehalase.

Biochemical Journal 353, 157-162  [ pubmed ]

Heiland S., Radovanovic N., Hofer M., Winderickx J. and Lichtenberg H.

Multiple hexose transporters of Schizosaccharomyces pombe.

Journal of Bacteriology 182, 2153-2162  [ pubmed ]

Kayingo G., Casaleggio C., Tamas M.J., Hohmann S. and Prior B.A.

An investigation of the possible existence of homologues of FPS1, a glycerol facilitator of Saccharomyces cerevisiae, in the osmotolerant yeast Zygosaccharomyces rouxii.

In Hohmann S. and Nielsen S. (eds.), Molecular biology and physiology of water and solute transport: Fundamental and applied aspects. Kluwer Academic/Plenum Publishers, New York, NY, pp. 393-403

Deeb S.S., Hayashi T., Winderickx J. and Yamaguchi T.

Molecular analysis of human red/green visual pigment gene locus: relationship to color vision.

Methods in Enzymology 316, 651-670  [ pubmed ]

Thevissen K., Cammue B.P., Lemaire K., Winderickx J., Dickson R.C., Lester R.L., Ferket K.K., Van Even F., Parret A.H. and Broekaert W.F.

A gene encoding a sphingolipid biosynthesis enzyme determines the sensitivity of Saccharomyces cerevisiae to an antifungal plant defensin from dahlia (Dahlia merckii).

Proceedings of the National Academy of Sciences U.S.A. 97, 9531-9536  [ pubmed ]

Thevelein J.M., Cauwenberg L., Colombo S., De Winde J.H., Donation M., Dumortier F., Kraakman L., Lemaire K., Ma P., Nauwelaers D., Rolland F., Teunissen A., Van Dijck P., Versele M., Wera S. and Winderickx J.

Nutrient-induced signal transduction through the protein kinase A pathway and its role in the control of metabolism, stress resistance, and growth in yeast.

Enzyme and Microbial Technology 26, 819-825  [ pubmed ]

Noubhani A., Bunoust O., Rigoulet M. and Thevelein J.M.

Reconstitution of ethanolic fermentation in permeabilized spheroplasts of wild-type and trehalose-6-phosphate synthase mutants of the yeast Saccharomyces cerevisiae.

Eur J Biochem. 267, 4566-4576  [ pubmed ]

Bonini B.M., Van Vaeck C., Larsson C., Gustafsson L., Ma P., Winderickx J., Van Dijck P. and Thevelein J.M.

Expression of escherichia coli otsA in a Saccharomyces cerevisiae tps1 mutant restores trehalose 6-phosphate levels and partly restores growth and fermentation with glucose and control of glucose influx into glycolysis.

Biochemical Journal 350, 261-268  [ pubmed ]

Van Hoof C., Janssens V., De Baere I., de Winde J.H., Winderickx J., Dumortier F., Thevelein J.M., Merlevede W. and Goris J.

The Saccharomyces cerevisiae homologue YPA1 of the mammalian phosphotyrosyl phosphatase activator of protein phosphatase 2A controls progression through the G1 phase of the yeast cell cycle.

Journal of Molecular Biology 302, 103-120  [ pubmed ]

Rolland F., De Winde J.H., Lemaire K., Boles E., Thevelein J.M. and Winderickx J.

Glucose-induced cAMP signalling in yeast requires both a G-protein coupled receptor system for extracellular glucose detection and a separable hexose kinase-dependent sensing process.

Molecular Microbiology 38, 348-358  [ pubmed ]

Van Dijck P., Ma P., Versele M., Gorwa M.F., Colombo S., Lemaire K., Bossi D., Loiez A. and Thevelein J.M.

A baker's yeast mutant (fil1) with a specific, partially inactivating mutation in adenylate cyclase maintains a high stress resistance during active fermentation and growth.

Journal of Molecular Microbiology and Biotechnology 2, 521-530  [ pubmed ]

Tamas M.J., Rep M., Thevelein J.M. and Hohmann S.

Stimulation of the yeast High Osmolarity Glycerol (HOG) pathway: evidence for a signal generated by a change in turgor rather than by water stress.

FEBS Letters 472, 159-165  [ pubmed ]

Eliasson A., Boles E., Johansson B., Osterberg M., Thevelein J.M., Spencer-Martins I., Juhnke H. and Hahn-Hagerdal B.

Xylulose fermentation by mutant and wild-type strains of Zygosaccharomyces and Saccharomyces cerevisiae.

Applied Microbiology and Biotechnology 53, 376-382  [ pubmed ]

Dumortier F., Vanhalewyn M., Debast G., Colombo S., Ma P., Winderickx J., Van Dijck P. and Thevelein J.M.

A specific mutation in Saccharomyces cerevisiae adenylate cyclase, Cyr1K1876M, eliminates glucose- and acidification-induced cAMP signalling and delays glucose-induced loss of stress resistance.

International Journal of Food Microbiology 55, 103-107  [ pubmed ]

Van Dijck P., Gorwa M.-F., Lemaire K., Teunissen A., Versele M., Colombo S., Dumortier F., Ma P., Tanghe A., Loiez A. and Thevelein J.M.

Characterization of a new set of mutants deficient in fermentation induced loss of stress resistance for use in frozen dough applications.

International Journal of Food Microbiology 55, 187-192  [ pubmed ]

Tanghe A., Teunissen A., Van Dijck P. and Thevelein J.M.

Identification of genes responsible for improved cryoresistance in fermenting yeast cells.

International Journal of Food Microbiology 55, 259-262  [ pubmed ]

Rep M., Krantz M., Thevelein J.M. and Hohmann S.

The transcriptional response of yeast to osmotic shock: Hot1p and Msn2p/Msn4p are required for the induction of subsets of Hog1p-dependent genes.

Journal of Biological Chemistry 275, 8290-8300  [ pubmed ]

Zahringer H., Thevelein J.M. and Nwaka S.

Induction of neutral trehalase Nth1 by heat and osmotic stress is controlled by STRE elements and Msn2/Msn4 transcription factors: variations of PKA effect during stress and growth.

Molecular Microbiology 35, 397-406  [ pubmed ]

Thevelein J.M., Cauwenberg L., Colombo S., de Winde J.H., Donaton M., Dumortier F., Kraakman L., Lemaire K., Ma P., Nauwelaers D., Rolland F., Teunissen A., Van Dijck P., Versele M., Wera S. and Winderickx J.

Nutrient-induced signal transduction through the protein kinase A pathway and its role in the control of metabolism, stress resistance and growth in yeast.

Enzyme and Microbial Technology. 26, 9-10  [ pubmed ]

Rep M., Reiser V., Gartner U., Thevelein J.M., Hohmann S., Ammerer G. and Ruis H.

Osmotic stress-induced gene expression in Saccharomyces cerevisiae requires Msn1p and the novel nuclear factor Hot1p.

Molecular and Cellular Biology 19, 5474-5485  [ pubmed ]

Van Vaeck C., Wera S., Bonini B., Van Dijck P. and Thevelein J.M.

Determination of trehalose-6-phosphate levels in Saccharomyces cerevisiae, using Bacillus subtilis phosphotrehalase. Proceedings of Forum for Applied Biotechnology '99

Mededelingen Fac. Landbouww. Univ. Gent 64/5B, 647-650

Versele M., de Winde J.H. and Thevelein J.M.

A novel regulator of G-protein signalling in yeast, Rgs2, downregulates glucose-activation of the cAMP pathway through direct inhibition of Gpa2.

EMBO Journal 18, 5577-5591  [ pubmed ]

Kraakman L., Lemaire K., Ma P., Teunissen A.W.R.H., Donaton M.C.V., Van Dijck P., Winderickx J., de Winde J.H. and Thevelein J.M.

A Saccharomyces cerevisiae G-protein coupled receptor, Gpr1, is specifically required for glucose activation of the cAMP pathway during the transition to growth on glucose.

Molecular Microbiology 32, 1002-1012  [ pubmed ]

Wera S., De Schrijver E.,Geyskens I. , Nwaka S. and Thevelein J.M.

Opposite roles of trehalase activity in heat-shock recovery and heat-shock survival in Saccharomyces cerevisiae.

Biochemical Journal 343, 621-626  [ pubmed ]

Wera S., Degreve B., Balzarini J., De Clercq E., Thevelein J.M. and Neyts J.

Budding yeast as a screening tool for discovery of nucleoside analogs for use in HSV-1 TK suicide gene therapy.

BioTechniques 27, 772-777  [ pubmed ]

Kraakman L.S., Winderickx J., Thevelein J.M. and de Winde J.H.

Structure-function analysis of yeast hexokinase: structural requirements for triggering cAMP signalling and catabolite repression.

Biochemical Journal 343, 159-168  [ pubmed ]

Ma P., Winderickx J., Nauwelaers D., Dumortier F., De Doncker A., Thevelein J.M. and Van Dijck P.

Deletion of SFI1, a novel suppressor of partial Ras-cAMP pathway deficiency in the yeast Saccharomyces cerevisiae, causes G2 arrest.

Yeast 15, 1097-1109  [ pubmed ]

Vanhalewyn M., Dumortier F., Debast G., Colombo S., Ma P., Winderickx J., Van Dijck P. and Thevelein J.M.

A mutation in Saccharomyces cerevisiae adenylate cyclase, Cyr1K1876M, specifically affects glucose- and acidification-induced cAMP signalling and not the basal cAMP level.

Molecular Microbiology 33, 363-376  [ pubmed ]

Thevelein J.M. and de Winde J.H.

Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae.

Molecular Microbiology 33, 904-918  [ pubmed ]

Rep M., Albertyn J., Thevelein J.M., Prior B.A. and Hohmann S.

Different signalling pathways contribute to the control of GPD1 gene expression by osmotic stress in Saccharomyces cerevisiae.

Microbiology 145, 715-727  [ pubmed ]

Tamas M.J., Luyten K., Sutherland F.C.W., Hernandez A., Albertyn J., Valadi H., Li H., Prior B.A., Kilian S.G., Ramos J., Gustafsson L., Thevelein J.M. and Hohmann S.

Fps1p controls the accumulation and release of the compatible solute glycerol in yeast osmoregulation.

Molecular Microbiology 31, 1087-1104  [ pubmed ]

Planta R.J., Brown A.J.P., Cadahia J.L., Cerdan M.E., De Jonge M., Gent M.E., Hayes A., Kolen C.P.A.M., Lombardia L.J., Sefton M., Oliver S.G., Thevelein J.M., Tournu H., van Delft Y.J., Verbart D.J. and Winderickx J.

Transcript analysis of 250 novel yeast genes from chromosome XIV.

Yeast 15, 329-350  [ pubmed ]

Zentella R., Mascorro-Gallardo J.O., Van Dijck P., Folch-Mallol J., Bonini B., Van Vaeck C., Gaxiola R., Covarrubias A.A., Nieto-Sotelo J., Thevelein J.M. and Iturriaga G.

A Selaginella lepidophylla trehalose-6-phosphate synthase complements growth and stress tolerance defects in a yeast tps1 mutant.

Plant Physiology 119, 1473-1482  [ pubmed ]

Hohmann S., Winderickx J., de Winde J.H., Valckx D., Cobbaert P., Luyten K., de Meirsman C., Ramos J. and Thevelein J.M.

Novel alleles of yeast hexokinase PII with distinct effects on catalytic activity and catabolite repression of SUC2.

Microbiology 145, 703-714  [ pubmed ]

Ma P., Wera S., Van Dijck P. and Thevelein J.M.

The PDE1 encoded low-affinity phosphodiesterase in the yeast Saccharomyces cerevisiae has a specific function in controlling agonist-induced cAMP signalling.

Molecular Biology of the Cell 10, 91-104  [ pubmed ]

Wera S.

An EXCEL-based method to search for potential Ser/Thr-phosphorylation sites in proteins.

Computer Methods and Programs in Biomedicine 58, 65-68

Hernandez A. and Ruiz M.T.

An EXCEL template for calculation of enzyme kinetic parameters by non-linear regression.

Bioinformatics 14, 227-228

Hohmann S. and Meacock P.A.

Thiamin metabolism and thiamindiphosphate dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation.

Biochimica et Biophysica Acta 1385, 201-219  [ pubmed ]

de Winde J.H., Kraakman L., Winderickx J. and Thevelein J.M.

Control of glycolytic influx monitored through site-directed mutagenesis of yeast hexokinase PII.

In: "BioThermoKinetics in the Post Genomic Era", C.Larsson, I.-L. P?hlman and L.Gustafsson (eds.), Chalmers, Goteborg. pp.250-255

Ernandes J.R., De Meirsman C., Rolland F., Winderickx J., de Winde J., Brandao R.L. and Thevelein J.M.

During the initiation of fermentation overexpression of hexokinase PII in yeast transiently causes a similar deregulation of glycolysis as deletion of Tps1.

Yeast 14, 255-269  [ pubmed ]

Hounsa C.-G., Brandt E.V., Thevelein J.M., Hohmann S. and Prior B.A.

Role of trehalose in survival of Saccharomyces cerevisiae under osmotic stress.

Microbiology 144, 671-680  [ pubmed ]

Bell W., Sun W., Hohmann S., Wera S., Reinders A., De Virgilio C., Wiemken A. and Thevelein J.M.

Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex.

Journal of Biological Chemistry 273, 33311-33319  [ pubmed ]

Colombo S., Ma P., Cauwenberg L., Winderickx J., Crauwels M., Teunissen A., Nauwelaers D., de Winde J.H., Gorwa M.-F., Colavizza D. and Thevelein J.M.

Involvement of distinct G-proteins, Gpa2 and Ras, in glucose- and intracellular acidification-induced cAMP signalling in the yeast Saccharomyces cerevisiae.

The EMBO Journal 17, 3326-3341  [ pubmed ]

Coccetti P., Tisi R., Martegani E., Teixeira L.S., Brandao R.L., Castro I.M. and Thevelein J.M.

The PLC1 encoded phospholipase C in the yeast Saccharomyces cerevisiae is essential for glucose-induced phosphatidylinositol turnover and activation of plasma membrane H+-ATPase.

Biochimica Biophysica Acta 1405, 147-154  [ pubmed ]

Sutherland F.C.W., Lages F., Lucas C., Luyten K., Albertyn J., Hohmann S., Prior B.A. and Kilian S.G.

Characteristics of Fps1-dependent and -independent glycerol transport in Saccharomyces cerevisiae.

Journal of Bacteriology 179, 7790-7795  [ pubmed ]

Hohmann S.

Pyruvate decarboxylases.

In: 'Yeast sugar metabolism: biochemistry, genetics, biotechnology and applications.' (F.K. Zimmermann & K.-D. Entian, eds.) Technomic Publishing Co., Lancaster, Pennsylvania, USA, pp.187-211

Hohmann S.

Shaping up: The response of yeast to osmotic stress.

In: 'Yeast stress responses', Hohmann S. and Mager W.H., eds., Molecular Biology Intelligence Unit, R.G. Landes Company, Austin, TX, 1997, pp. 101-145

Mager W.H. and Hohmann S.

Introduction: Stress response mechanisms in the yeast Saccharomyces cerevisiae.

In: 'Yeast stress responses', Hohmann S. and Mager W.H., eds., Molecular Biology Intelligence Unit, R.G. Landes Company, Austin, TX, 1997, pp. 1-5

Hohmann S. and Mager W.H. (Editors)

Yeast stress responses.

Molecular Biology Intelligence Unit. Landes Company. 252 pages. ISBN: 3-540-62040-0

Hohmann S.

Glycerol production and osmoregulation.

In: 'Yeast sugar metabolism: biochemistry, genetics, biotechnology and applications.' (F.K. Zimmermann and K.-D. Entian, eds.) Technomic Publishing Co., Lancaster, PA, USA. p. 313-337

Prior B.A. and Hohmann S.

Glycerol production and osmoregulation.

In: 'Yeast sugar metabolism: biochemistry, genetics, biotechnology and applications.' (F.K. Zimmermann and K.-D. Entian, eds.) Technomic Publishing Co., Lancaster, PA, USA

Reinders A., Burckert N., Hohmann S., Thevelein J.M., Boller T., Wiemken A. and De Virgilio C.

Structural analysis of the subunits of the trehalose-6-phosphate synthase/phosphatase complex in Saccharomyces cerevisiae and their function during heat shock.

Molecular Microbiology 24, 687-695  [ pubmed ]

Wanke V., Vavassori M., Thevelein J.M., Tortora P. and Vanoni M.

Regulation of maltose utilization in Saccharomyces cerevisiae by genes of the RAS/protein kinase A pathway.

FEBS Letters 402, 251-255  [ pubmed ]

Crauwels M., Donaton M.C.V., Pernambuco M.B., Winderickx J., de Winde J.H. and Thevelein J.M.

The Sch9 protein kinase in the yeast Saccharomyces cerevisiae controls cAPK activity and is required for nitrogen activation of the fermentable-growth-medium-induced (FGM) pathway.

Microbiology 143, 2627-2637  [ pubmed ]

Ma P., Goncalves T., Maretzek A., Loureiro-Dias M.C. and Thevelein J.M.

The lag phase rather than the exponential-growth phase on glucose is associated with a higher cAMP level in wild-type and cAPK-attenuated strains of the yeast Saccharomyces cerevisiae.

Microbiology 143, 3451-3459  [ pubmed ]

Jorge J.A., de Lourdes M. Polizeli T.M., Thevelein J.M. and Terenzi H.F.

Trehalases and trehalose hydrolysis in fungi.

FEMS Microbiology Letters 154, 165-171  [ pubmed ]

Ferreira J.C., Thevelein J.M., Hohmann S., Paschoalin V.M., Trugo L.C. and Panek A.D.

Trehalose accumulation in mutants of Saccharomyces cerevisiae deleted in the UDPG-dependent trehalose synthase-phosphatase complex.

Biochimica Biophysica Acta 1335, 40-50  [ pubmed ]

Crauwels M., Winderickx J., de Winde J.H. and Thevelein J.M.

Identification of genes with nutrient-controlled expression by PCR-mapping in the yeast Saccharomyces cerevisiae.

Yeast 13, 973-984  [ pubmed ]

de Winde J.H., Thevelein J.M. and Winderickx J.

From feast to famine: adaptation to nutrient depletion in yeast.

In: 'Yeast stress responses', Hohmann S. and Mager W.H., eds., Molecular Biology Intelligence Unit, R.G. Landes Company, Austin, TX, 1997, pp. 7-52

Ansell R., Granath K., Hohmann S., Thevelein J.M. and Adler L.

The two isoenzymes for yeast NAD+-dependent glycerol 3-phosphate dehydrogenase encoded by GPD1 and GPD2 have distinct roles in osmoadaptation and redox regulation.

The EMBO Journal 16, 2179-2187  [ pubmed ]

Wera S., Ma P. and Thevelein J.M.

Glucose exerts opposite effects on mRNA versus protein and activity levels of Pde1, the low-affinity cAMP phosphodiesterase from budding yeast Saccharomyces cerevisiae.

FEBS Letters 420, 147-150  [ pubmed ]

Amaral F.C., Van Dijck P., Nicoli J.R. and Thevelein J.M.

Molecular cloning of the neutral trehalase gene from Kluyveromyces lactis and the distinction between neutral and acid trehalases.

Archives of Microbiology 167, 202-208  [ pubmed ]

Boles E., Zimmermann F.K. and Thevelein J.M.

Metabolic signals.

In: 'Yeast sugar metabolism: biochemistry, genetics, biotechnology and applications.' (F.K. Zimmermann & K.-D. Entian, eds.) Technomic Publishing Co., Lancaster, Pennsylvania, USA, pp.379-407

Gomez M.J., Luyten K. and Ramos J.

The capacity to transport potassium influences sodium tolerance in Saccharomyces cerevisiae.

FEMS Microbiology Letters 135, 157-160  [ pubmed ]

Killenberg-Jabs M., Eberhardt I., Konig S., Hohmann S. and Hubner G.

Investigation of the cofactor interaction in pyruvate decarboxylase by site-directed mutagenesis.

In: Biochemistry and physiology of thiamin diphosphate enzymes. (Bisswanger H. & A. Schellenberger, eds.) pp.141-150

Jordan F., Baburina I., Gao Y., Guo F., Kahyaoglu A., Nemeria N., Volkov A.,. Yi J.-Z, Zhang D., Machado R., Guest J.R., Furey W. and Hohmann S.

New insights to the regulation of thiamin diphosphate-dependent decarboxylases by substrate and ThDP.Mg(II).

In: Biochemistry and physiology of thiamin diphosphate enzymes. (Bisswanger H. & A. Schellenberger, eds.) pp.53-56

Eberhardt I. and Hohmann S.

Autoregulation of pyruvate decarboxylase gene expression in Saccharomyces cerevisiae.

In: Biochemistry and physiology of thiamin diphosphate enzymes. (Bisswanger H. & A. Schellenberger, eds.) pp.134-140

Hohmann S., Eberhardt I., Muller E. and Pretorius G.H.J.

Control of the synthesis of pyruvate decarboxylase in yeast.

In: Biochemistry and physiology of thiamin diphosphate enzymes. (Bisswanger H. & A. Schellenberger, eds.) pp.125-133

Killenberg-Jabs M., Konig S., Hohmann S. and Hubner G.

Purification and characterisation of the pyruvate decarboxylase from a haploid strain of Saccharomyces cerevisiae.

Biological Chemistry Hoppe-Seyler 377, 313-317  [ pubmed ]

Hohmann S., Bell W., Neves M.J., Valckx D. and Thevelein J.M.

Evidence for trehalose-6-phosphate-dependent and -independent mechanisms in the control of sugar influx into yeast glycolysis.

Molecular Microbiology 20, 981-991  [ pubmed ]

de Winde J.H., Crauwels M., Hohmann S., Thevelein J.M. and Winderickx J.

Differential requirement of the yeast sugar kinases for sugar sensing in establishing the catabolite-repressed state.

European Journal of Biochemistry 241, 633-643  [ pubmed ]

Winderickx J., de Winde J.H., Crauwels M., Hino A., Hohmann S., Van Dijck P. and Thevelein J.M.

Regulation of genes encoding subunits of the trehalose synthase complex in Saccharomyces cerevisiae: novel variations of STRE-mediated transcription control ?

Molecular and General Genetics 252, 470-482  [ pubmed ]

Pernambuco M.B., Winderickx J., Crauwels M., Griffioen G., Mager W.H. and Thevelein J.M.

Glucose-triggered signalling in Saccharomyces cerevisiae : different requirements for sugar phosphorylation between cells grown on glucose and those grown on non-fermentable carbon sources.

Microbiology 142, 1775-1782  [ pubmed ]

Thevelein J.M.

Regulation of trehalose metabolism and its relevance to cell growth and function.

In: The Mycota : A Treatise on the Biology of Fungi with Emphasis on Systems for Fundamental and Applied Research. (K. Esser and P.A. Lemke, eds.) Vol. III Biochemistry and Molecular Biology (R. Brambl and G.A. Marzluf, eds.) Chapter 19, p.395-420

Thevelein J.M. and Hohmann S.

Reply to a letter to the editor.

Trends in Biochemical Sciences, Electronic Newsgroup

Thevelein J.M.

Ouro Preto, Brazil: Practical course on molecular biology of micro-organisms.

Society of General Microbiology Quarterly, February 1995, Vol. 22 Part 1 pp. 10-12

Eberhardt I. and Hohmann S.

Strategy for deletion of complete open reading frames in Saccharomyces cerevisiae.

Current Genetics 27, 306-308  [ pubmed ]

Dumortier F., Arguelles J.-C. and Thevelein J.M.

Constitutive glucose-induced activation of the Ras-cAMP pathway and aberrant stationary-phase entry on a glucose-containing medium in the Saccharomyces cerevisiae glucose-repression mutant hex2.

Microbiology 141, 1559-1566  [ pubmed ]

Luyten K., Albertyn J., Skibbe W.F., Prior B.A., Ramos J., Thevelein J.M. and Hohmann S.

Fps1, a yeast member of the MIP family of channel proteins, is a facilitator for glycerol uptake and efflux and is inactive under osmotic stress.

The EMBO Journal 14, 1360-1371  [ pubmed ]

Van Dijck P., Colavizza D., Smet P. and Thevelein J.M.

Differential importance of trehalose in stress resistance in fermenting and nonfermenting Saccharomyces cerevisiae cells.

Applied and Environmental Microbiology 61, 109-115  [ pubmed ]

Thevelein J.M. and Hohmann S.

Trehalose synthase: guard to the gate of glycolysis in yeast ?

Trends in Biochemical Sciences 20, 3-10  [ pubmed ]

Neves M.J., Hohmann S., Bell W., Dumortier F., Luyten K., Ramos J., Cobbaert P., de Koning W., Kaneva Z. and Thevelein J.M.

Control of glucose influx into glycolysis and pleiotropic effects studied in different isogenic sets of Saccharomyces cerevisiae mutants in trehalose biosynthesis.

Current Genetics 27, 110-122  [ pubmed ]

Baburina I., Gao Y., Hu Z., Jordan F., Hohmann S. and Furey W.

Substrate activation of brewer's yeast pyruvate decarboxylase is abolished by mutation of cysteine 221 to serine.

Biochemistry 33, 5630-5635  [ pubmed ]

Albertyn J., Hohmann S. and Prior B.A.

Characterization of the osmotic-stress response in Saccharomyces cerevisiae: osmotic stress and glucose repression regulate glycerol-3-phosphate dehydrogenase independently.

Current Genetics 25, 12-18  [ pubmed ]

Thevelein J.M.

Signal transduction in yeast.

Yeast 10, 1753-1790  [ pubmed ]

Hohmann S., Van Dijck P., Luyten K. and Thevelein J.M.

The byp1-3 allele of the Saccharomyces cerevisiae GGS1/TPS1 gene and its multi copy suppressor tRNAGLN (CAG): Ggs1/Tps1 protein levels restraining growth on fermentable sugars and trehalose accumulation.

Current Genetics 26, 295-301  [ pubmed ]

Albertyn J., Hohmann S., Thevelein J.M. and Prior B.A.

GPD1, which encodes glycerol-3-phosphate dehydrogenase is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the High-Osmolarity Glycerol response pathway.

Molecular and Cellular Biology 14, 4135-4144  [ pubmed ]

Durnez P., Pernambuco M.B., Oris E., Arguelles J.-C., Mergelsberg H. and Thevelein J.M.

Activation of trehalase during growth induction by nitrogen sources in the yeast Saccharomyces cerevisiae depends on the free catalytic subunits of cAMP-dependent protein kinase, but not on functional Ras proteins.

Yeast 10, 1049-1064  [ pubmed ]

Brandao R.L., de Magalhaes-Rocha N.M., Alijo R., Ramos J. and Thevelein J.M.

Possible involvement of a phosphatidylinositol-type signaling pathway in glucose-induced activation of plasma membrane H+-ATPase and cellular proton extrusion in the yeast Saccharomyces cerevisiae.

Biochimica et Biophysica Acta 1223, 117-124  [ pubmed ]

Hohmann S.

Characterisation of PDC2, a gene necessary for high level expression of puruvate decarboxylase structural genes in Saccharomyces cerevisiae.

Molecular and General Genetics 241, 657-666

Zeng X.P., Farrenkopf B., Hohmann S., Dyda F., Furey W. and Jordan F.

Role of cysteines in the activation and inactivation of brewer's yeast pyruvate decarboxylase investigated with a PDC1-PDC6 fusion protein.

Biochemistry 32, 2704-2709  [ pubmed ]

Luyten K., de Koning W., Tesseur I., Ruiz M.C., Ramos J., Cobbaert P., Thevelein J.M. and Hohmann S.

Disruption of the Kluyveromyces lactis GGS1 gene causes inability to grow on glucose and fructose and is suppressed by mutations that reduce sugar uptake.

European Journal of Biochemistry 217, 701-713  [ pubmed ]

Kraakman L.S., Griffioen G., Zerp S., Groeneveld P., Thevelein J.M., Mager W.H. and Planta R.J.

Growth-related expression of ribosomal protein genes in Saccharomyces cerevisiae.

Molecular and General Genetics 239, 196-204  [ pubmed ]

Hohmann S., Neves M.J., de Koning W., Alijo R., Ramos J. and Thevelein J.M.

The growth and signalling defects of the ggs1 (fdp1/byp1) deletion mutant on glucose are suppressed by a deletion of the gene encoding hexokinase PII.

Current Genetics 23, 281-289  [ pubmed ]

Van Aelst L., Hohmann S., Bulaya B., de Koning W., Sierkstra L., Neves M.J., Luyten K., Alijo R., Ramos J., Coccetti P., Martegani E., de Magalhaes-Rocha N.M., Brandao R.L., Van Dijck P., Vanhalewyn M., Durnez P., Jans A.W.H. and Thevelein J.M.

Molecular cloning of a gene involved in glucose sensing in the yeast Saccharomyces cerevisiae.

Molecular Microbiology 8, 927-943  [ pubmed ]

Hohmann S.

Der Kohlenhydratstoffwechsel der Hefe Saccharomyces cerevisiae. Teil 2. Regulation.

BIOforum 15, 59-63

Hohmann S.

Der Kohlenhydratstoffwechsel der Hefe Saccharomyces cerevisiae. Teil 1. Genetik.

BIOforum 15, 4-9

Hohmann S. and Thevelein J.M.

The cell division cycle gene CDC60 encodes the cytosolic leucyl-tRNA synthetase in Saccharomyces cerevisiae.

Gene 120, 43-49  [ pubmed ]

Hirimburegama K., Durnez P., Keleman J., Oris E., Vergauwen R., Mergelsberg H. and Thevelein J.M.

Nutrient-induced activation of trehalase in nutrient-starved cells of the yeast Saccharomyces cerevisiae. cAMP is not involved as second messenger.

Journal of General Microbiology 138, 2035-2043  [ pubmed ]

Hohmann S., Huse K., Valentin E., Mbonyi K., Thevelein J.M. and Zimmermann F.K.

Glucose-induced regulatory defects in the Saccharomyces cerevisiae byp1 growth initiation mutant and identification of MIG1 as a partial suppressor.

Journal of Bacteriology 174, 4183-4188  [ pubmed ]

Brandao R.L., Castro I.M., Passos J.B., Nicoli J.R. and Thevelein J.M.

Glucose-induced activation of the plasma membrane H+-ATPase in Fusarium oxysporum.

Journal of General Microbiology 138, 1579-1586  [ pubmed ]

Becher dos Passos J., Vanhalewyn M., Brandao R. L., Castro I. M., Nicoli J.R. and Thevelein J.M.

Glucose-induced activation of plasma membrane H+-ATPase in mutants of the yeast Saccharomyces cerevisiae affected in cAMP metabolism, cAMP-dependent protein phosphorylation and the initiation of glycolysis.

Biochimica et Biophysica Acta 1136, 57-67  [ pubmed ]

Thevelein J.M.

The RAS-adenylate cyclase pathway and cell cycle control in Saccharomyces cerevisiae.

Antonie van Leeuwenhoek, Journal of Microbiology. Special Issue: 'Molecular Biology of Yeasts' (L. Grivell ed., Kluwer, Dordrecht) 62, 109-130  [ pubmed ]

Hohmann S.

PDC6, a weakly expressed pyruvate decarboxylase gene from yeast, is activated when fused spontaneously under the control of the PDC1promotor.

Current Genetics 20, 373-378  [ pubmed ]

Hohmann S.

Characterization of PDC6, a third structural gene for pyruvate decarboxylase in Saccharomyces cerevisiae.

Journal of Bacteriology 173, 7963-7969  [ pubmed ]

Van Aelst L., Hohmann S., Zimmermann F.K., Jans A.W.H. and Thevelein J.M.

A yeast homologue of the bovine lens fibre MIP gene family complements the growth defect of a Saccharomyces cerevisiae mutant on fermentable sugars but not its defect in glucose-induced RAS-mediated cAMP signalling.

The EMBO Journal 10, 2095-2104  [ pubmed ]

Thevelein J.M.

Fermentable sugars and intracellular acidification as specific activators of the RAS-adenylate cyclase signalling pathway in yeast: the relationship to nutrient-induced cell cycle control.

Molecular Microbiology 5, 1301-1307  [ pubmed ]

Van Aelst L., Jans A.W.H. and Thevelein J.M.

Involvement of the CDC25 gene product in the signal transmission pathway of the glucose-induced RASmediated cAMP signal in the yeast Saccharomyces cerevisiae.

Journal of General Microbiology 137, 341-349  [ pubmed ]

Van Aelst L., Boy-Marcotte E., Camonis J.H., Thevelein J.M. and Jacquet M.

The C-terminal part of the CDC25 gene product plays a key role in signal transduction in the glucose-induced modulation of cAMP level in Saccharomyces cerevisiae.

European Journal of Biochemistry 193, 675-680  [ pubmed ]

Arguelles J.C., Mbonyi K., Van Aelst L., Vanhalewyn M., Jans A.W.H. and Thevelein J.M.

Absence of glucose-induced cAMP signaling in the Saccharomyces cerevisiae mutants cat1 and cat3 which are deficient in derepression of glucose-repressible proteins.

Archives of Microbiology 154, 199-205  [ pubmed ]

Mbonyi K., Van Aelst L., Arguelles J.C., Jans A.W.H. and Thevelein J.M.

Glucose-induced hyperaccumulation of cyclic AMP and defective glucose repression in yeast strains with reduced activity of cyclic AMP-dependent protein kinase.

Molecular and Cellular Biology 10, 4518-4523  [ pubmed ]

Beullens M. and Thevelein J.M.

Investigation of transport-associated phosphorylation of sugar in yeast mutants (snf3) lacking high-affinity glucose transport and in a mutant (fdp1) showing deficient regulation of initial sugar metabolism.

Current Microbiology 21, 39-46

Hemschoote K., Peeters B., Dirckx L., Claessens F., De Clercq M., Heyns W., Winderickx J., Bannwarth W. and Rombauts W.

A single 12.5 kilobase androgen-regulated mRNA encoding multiple proline-rich polypeptides in the ventral prostate of the rat.

Journal of Biological Chemistry 263, 19159-19165  [ pubmed ]

Mbonyi K. and Thevelein J.M.

The high-affinity glucose uptake system is not required for induction of the RAS-mediated cAMP signal by glucose in cells of the yeast Saccharomyces cerevisiae.

Biochimica et Biophysica Acta 971, 223-226  [ pubmed ]

Mbonyi K., Beullens M., Detremerie K., Geerts L. and Thevelein J.M.

Requirement of one functional RAS gene and inability of an oncogenic ras variant to mediate the glucose-induced cAMP signal in the yeast Saccharomyces cerevisiae.

Molecular and Cellular Biology 8, 3051-3057  [ pubmed ]

Thevelein J.M.

Regulation of trehalase activity by phosphorylation-dephosphorylation during developmental transitions in fungi.

Experimental Mycology 12, 1-12

Beullens M., Mbonyi K., Geerts L., Gladines D., Detremerie K., Jans A.W.H. and Thevelein J.M.

Studies on the mechanism of the glucose-induced cAMP-signal in glycolysis- and glucose repression-mutants of the yeast Saccharomyces cerevisiae.

European Journal of Biochemistry 172, 227-231  [ pubmed ]

Van Dijck P., Lemaigre F.P., Winderickx J., Rousseau G. and Verhoeven G.

Glucocorticoid receptor binding to defind regions of the alpha-2-urinary globulin genes.

Biochemical and Biophysical Research Communications 149, 1099-1105  [ pubmed ]

Winderickx J., Van Dijck P., Dirckx L., Volckaert G., Rombauts W., Heyns W. and Verhoeven G.

Comparison of the 5' upstream regulatory sequences of 3 members of the alpha-2-urinary globulin gene family.

European Journal of Biochemistry 165, 521-529  [ pubmed ]

Thevelein J.M., Beullens M., Honshoven F., Hoebeeck G., Detremerie K., Griewel B., den Hollander J.A. and Jans A.W.H.

Regulation of the cAMP level in the yeast Saccharomyces cerevisiae : the glucose-induced cAMP signal is not mediated by a transient drop in the intracellular pH.

Journal of General Microbiology 133, 2197-2205  [ pubmed ]

Thevelein J.M., Beullens M., Honshoven F., Hoebeeck G., Detremerie K., den Hollander J.A. and Jans A.W.H.

Regulation of the cAMP level in the yeast Saccharomyces cerevisiae : Intracellular pH and the effect of membrane depolarizing compounds.

Journal of General Microbiology 133, 2191-2196  [ pubmed ]

Thevelein J.M. and Beullens M.

Cyclic-AMP and the stimulation of trehalase activity in the yeast Saccharomyces cerevisiae by carbon sources, nitrogen sources and inhibitors of protein synthesis.

Journal of General Microbiology 131, 3199-3209  [ pubmed ]

Thevelein J.M.

Regulation of trehalose mobilization in fungi.

Microbiological Reviews 48, 42-59  [ pubmed ]

Thevelein J.M.

Activation of trehalase by heat shock in yeast ascospores. Correlation with total cellular cyclic-AMP content.

Current Microbiology 10, 159-164  [ pubmed ]

Thevelein J.M.

Cyclic-AMP content and trehalase activation in vegetative cells and ascospores of yeast.

Archives of Microbiology 138, 64-67  [ pubmed ]

Thevelein J.M.

Activation of trehalase by membrane depolarizing agents in yeast vegetative cells and ascospores.

Journal of Bacteriology 158, 337-339  [ pubmed ]

Thevelein J.M., den Hollander J.A. and Shulman R.G.

Trehalase and the control of dormancy and induction of germination in fungal spores.

Trends in Biochemical Sciences 9, 495-497

Thevelein J.M. and Jones K.-A.

Reversibility characteristics of glucose-induced trehalase activation associated with the breaking of dormancy in yeast ascospores.

European Journal of Biochemistry 136, 583-587  [ pubmed ]

Thevelein J.M.

Investigation into the biochemical mechanisms involved in the induction of germination in Phycomyces blakesleeanus sporangiospores and yeast ascospores.

Academiae Analecta 45, 67-107

Thevelein J.M., Van Assche J.A. and Carlier A.R.

Isopropyl - substituted phenols have a different effect from other phenols on the breaking of dormancy by heat shok in Phycomyces blakesleeanus spores.

Journal of General Microbiology 129, 727-733

Thevelein J.M., Van Laere A.J., Beullens M., Van Assche J.A. and Carlier A.R.

Glucose-induced trehalase activation and trehalose mobilization during early germination of Phycomyces blakesleeanus spores.

Journal of General Microbiology 129, 719-726

Thevelein J.M., den Hollander J.A. and Shulman R.G.

Changes in the activity and properties of trehalase during early germination of yeast ascospores. Correlation with trehalose breakdown as studied by in vivo ¹³C NMR.

Proceedings of the National Academy of Sciences (USA) 79, 3503-3507  [ pubmed ]

Thevelein J.M., Van Assche J.A., Heremans K., Gerlsma S.Y. and Carlier A.R.

Trehalase activity in extracts of Phycomyces blakesleeanus spores following the induction of germination by heat activation.

Antonie van Leeuwenhoek 47, 393-404  [ pubmed ]

Thevelein J.M., Van Assche J.A., Heremans K. and Gerlsma S.Y.

Gelatinisation temperature of starch, as influenced by high pressure.

Carbohydrate Research 93, 304-307

Thevelein J.M., Van Assche J.A. and Heremans K.

Effect of high pressure on the heat activation in vivo of trehalase in the spores of Phycomyces blakesleeanus.

European Journal of Biochemistry 111, 171-175  [ pubmed ]

Thevelein J.M.,Van Assche J.A., Carlier A.R. and Heremans K.

Heat activation of Phycomyces blakesleeanus spores: theromdynamics and effect of alcohols, furfural, and high pressure.

Journal of Bacteriology 139, 478-485  [ pubmed ]