Thanks to key scientific advances and lifestyle interventions, humans worldwide are living longer. However, the icing on the longevity-cake is not there for everyone to enjoy: some of us age gracefully, whereas others spend several of their later years in poor health. These differences between individuals arise from a combination of genetic and environmental factors, ultimately affecting numerous molecular signaling pathways. The interplay of such changes throughout our entire lives affects the process of aging. Our team is captivated by the molecular mechanisms underlying differences in speed and health of aging.
Because it would take more than a lifetime to study human aging, we rely on the tiny nematode, C. elegans, to study interventions that affect life- and healthspan.
With a convenient lifespan of only ~3 weeks, evolutionary conservation of relevant mechanisms, and an excitingly large genetic and phenotypic toolbox, C. elegans is quite a star in this research field.
- Find out more about C. elegans here.
Relying on this model organism, we use all the genetic, phenotypic and -omics methods deemed necessary to answer our specific questions - or we develop new methods when needed. We currently have a special interest in peptidomics methods.
- Find out more about our ongoing research here.
All lab members contribute to theoretical courses and/or practical sessions aimed at students of Biology, Biochemistry & Biotechnology, Bio-informatics, Bio-engineering, Biomedical and Life Sciences.
Every year, we are joined by several students who learn how to conduct fundamental scientific research in light of their thesis projects or internships.
Are you looking for a place to conduct your Academic Ma, Academic Ba or Professional Ba project work? Take a look at your colleagues' current project topics here.
Our core team is made up of postdocs and PhD students. In addition, we host visiting scientists and train Master and Bachelor students. Core team members each have an individual research focus.
- Find out more about team member's individual interests here.
We are an enthusiastic research team, located in the historical center of Leuven (Belgium), a vibrant student city in the heart of Europe.
- Do you also want to make a significant change to our understanding of healthy aging?
- Do you want to be part of an internationally oriented, academic research team?
- Are you a motivated researcher with a background in Life Sciences, e.g. Biology, (Bio)Chemistry or (Bio)Engineering?
You might be our next +1 on the team!
Molecular and Functional Neurobiology
Naamsestraat 59 - box 2465