Publications

2011

 

  • Peeters L, Janssen T, De Haes W, Beets I, Meelkop E, Grant W, Schoofs L. (2011) A pharmacological study of NLP-12 neuropeptide signaling in free-living and parasitic nematodes. Peptides. 2011 Oct 14. [Epub ahead of print]
  • Temmerman L, Bogaerts A, Meelkop E, Cardoen D, Boerjan B, Janssen T, Schoofs L. (2011) A proteomic approach to neuropeptide function elucidation. Peptides. 2011 Sep 6. [Epub ahead of print]
  • Cardoen D, Wenseleers T, Ernst UR, Danneels EL, Laget D, DE Graaf DC, Schoofs L, Verleyen P. (2011) Genome-wide analysis of alternative reproductive phenotypes in honeybee workers. Mol Ecol. 2011 Oct;20(19):4070-84. doi: 10.1111/j.1365-294X.2011.05254.x. Epub 2011 Sep 9.
  • Boerjan B, Vandingenen K, De Loof A, Schoofs L. (2011) In search for non-steroidogenic functions of the prothoracic glands of the desert locust, Schistocerca gregaria: A peptidomic and proteomic approach. Peptides. 2011 Jul 30. [Epub ahead of print]
  • Cardoen D, Ernst UR, Van Vaerenbergh M, Boerjan B, de Graaf DC, Wenseleers T, Schoofs L, Verleyen P. (2011) Differential proteomics in dequeened honeybee colonies reveals lower viral load in hemolymph of fertile worker bees. PLoS One. 2011;6(6):e20043.
  • Boerjan B, Sas F, Ernst UR, Tobback J, Lemière F, Vandegehuchte MB, Janssen CR, Badisco L, Marchal E, Verlinden H, Schoofs L, De Loof A. (2011) Locust phase polyphenism: Does epigenetic precede endocrine regulation? Gen Comp Endocrinol. 2011 Aug 1;173(1):120-8.
  • Badisco L, Huybrechts J, Simonet G, Verlinden H, Marchal E, Huybrechts R, Schoofs L, De Loof A, Vanden Broeck J. (2011)  Transcriptome analysis of the desert locust central nervous system: production and annotation of a Schistocerca gregaria EST database. PLoS One. 2011 Mar 21;6(3):e17274.
  • Stirman JN, Crane MM, Husson SJ, Wabnig S, Schultheis C, Gottschalk A, Lu H. (2011) Real-time multimodal optical control of neurons and muscles in freely behaving Caenorhabditis elegans. Nat Methods. 2011 Feb;8(2):153-8.
  • Temmerman L, Meelkop E, Janssen T, Bogaerts A, Lindemans M, Husson SJ, Beets I, Schoofs L. (2011) C. elegans homologs of insect clock proteins: a tale of many stories. Ann N Y Acad Sci.  Mar;1220(1):137-48.
  • Van Dijck A, Hayakawa E, Landuyt B, Baggerman G, Van Dam D, Luyten W, Schoofs L, De Deyn PP. (2011) Comparison of extraction methods for peptidomics analysis of mouse brain tissue. J Neurosci Methods. 2011 Apr 30;197(2):231-7.
  • Boerjan B, Tobback J, De Loof A, Schoofs L, Huybrechts R.(2011) Fruitless RNAi knockdown in males interferes with copulation success in Schistocerca gregaria. Insect Biochem Mol Biol. 2011; 41(5): 340-347.
  • Boerjan B, De Loof A, Tanaka S, Schoofs L.(2011) Dispersion of peptides in vegetable oil as a simple slow release formula for both injection and oral uptake in insects: A case study with [His7]-corazonin in an albino Locusta migratoria deficient in corazonin. Peptides. 2011 Jul;32(7):1536-9.

 

2010

  • Meelkop E, Temmerman L, Schoofs L, Janssen T.(2010) Signalling through pigment dispersing hormone-like peptides in invertebrates. Prog Neurobiol. 2011 Jan;93(1):125-47.
  • Haenen S, Vanoirbeek JA, De Vooght V, Maes E, Schoofs L, Nemery B, Hoet PH, Clynen E. (2010) Proteome analysis of multiple compartments in a mouse model of chemical-induced asthma. J Proteome Res. 2010 Nov 5;9(11):5868-76.
  • Janssen T, Lindemans M, Meelkop E, Temmerman L, Schoofs L. (2010) Coevolution of neuropeptidergic signaling systems: from worm to man. Ann N Y Acad Sci. 2010 Jul;1200:1-14.
  • Mathy A, Baldo A, Schoofs L, Cambier L, Defaweux V, Tabart J, Maréchal F, Symoens F, Mignon B. (2010) Fungalysin and dipeptidyl-peptidase gene transcription in Microsporum canis strains isolated from symptomatic and asymptomatic cats. Vet Microbiol. 2010 Nov 20;146(1-2):179-82.
  • Menschaert G, Vandekerckhove TT, Baggerman G, Schoofs L, Luyten W, Van Criekinge W. (2010) Peptidomics coming of age: a review of contributions from a bioinformatics angle. J Proteome Res. 2010 May 7;9(5):2051-61. Review.
  • De Loof A, Huybrechts J, Geens M, Vandersmissen T, Boerjan B, Schoofs L. (2010) Sexual differentiation in adult insects: male-specific cuticular yellowing in Schistocerca gregaria as a model for reevaluating some current (neuro)endocrine concepts. J Insect Physiol. 2010 Aug;56(8):919-25.
  • Bogaerts A, Beets I, Temmerman L, Schoofs L, Verleyen P. (2010) Proteome changes of Caenorhabditis elegans upon a Staphylococcus aureus infection. Biol Direct. 2010 Feb 17;5:11.
  • Bogaerts A, Temmerman L, Boerjan B, Husson SJ, Schoofs L, Verleyen P. (2010) A differential proteomics study of Caenorhabditis elegans infected with Aeromonas hydrophila. Dev Comp Immunol. 2010 Jun;34(6):690-8.
  • Roelants K, Fry BG, Norman JA, Clynen E, Schoofs L, Bossuyt F. (2010 Identical skin toxins by convergent molecular adaptation in frogs. Curr Biol. 2010 Jan 26;20(2):125-30.
  • Clynen E, Liu F, Husson SJ, Landuyt B, Hayakawa E, Baggerman G, Wets G, Schoofs L. (2010) Bioinformatic approaches to the identification of novel neuropeptide precursors. Methods Mol Biol. 2010;615:357-74.
  • Boonen K, Husson SJ, Landuyt B, Baggerman G, Hayakawa E, Luyten WH, Schoofs L. (2010) Identification and relative quantification of neuropeptides from the endocrine tissues. Methods Mol Biol. 2010;615:191-206.
  • Husson SJ, Clynen E, Boonen K, Janssen T, Lindemans M, Baggerman G, Schoofs L. (2010) Approaches to identify endogenous peptides in the soil nematode Caenorhabditis elegans. Methods Mol Biol. 2010;615:29-47.
  • Menschaert G, Vandekerckhove TT, Baggerman G, Landuyt B, Sweedler JV, Schoofs L, Luyten W, Van Criekinge W. (2010) A hybrid, de novo based, genome-wide database search approach applied to the sea urchin neuropeptidome. J Proteome Res. 2010 Feb 5;9(2):990-6.
  • Boerjan B, Verleyen P, Huybrechts J, Schoofs L, De Loof A. (2010) In search for a common denominator for the diverse functions of arthropod corazonin: a role in the physiology of stress? Gen Comp Endocrinol. 2010 Apr 1;166(2):222-33.
  • Boerjan B, Cardoen D, Bogaerts A, Landuyt B, Schoofs L, Verleyen P. (2010) Mass spectrometric profiling of (neuro)-peptides in the worker honeybee, Apis mellifera. Neuropharmacology. 2010 Jan;58(1):248-58.  

2009

  • Sumakovic M, Hegermann J, Luo L, Husson SJ, Schwarze K, Olendrowitz C, Schoofs L, Richmond J, Eimer S. (2009) UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans. J Cell Biol., 186(6):897-914.
  • Bogaerts A, Baggerman G, Vierstraete E, Schoofs L, Verleyen P. (2009) The hemolymph proteome of the honeybee: gel-based or gel-free? Proteomics, 9(11):3201-8.
  • Reumer A, Bogaerts A, Van Loy T, Husson SJ, Temmerman L, Choi C, Clynen E, Hassan B, Schoofs L. (2009) Unraveling the protective effect of a Drosophila phosphatidylethanolamine-binding protein upon bacterial infection by means of proteomics. Dev Comp Immunol., 33(11):1186-95.
  • Paulussen M, Landuyt B, Schoofs L, Luyten W, Arckens L. (2009) Thymosin beta 4 mRNA and peptide expression in phagocytic cells of different mouse tissues. Peptides, 30(10):1822-32.
  • Janssen T, Husson SJ, Meelkop E, Temmerman L, Lindemans M, Verstraelen K, Rademakers S, Mertens I, Nitabach M, Jansen G, Schoofs L. (2009) Discovery and characterization of a conserved pigment dispersing factor-like neuropeptide pathway in Caenorhabditis elegans. J Neurochem., 111(1):228-41.
  • Janssen T, Meelkop E, Nachman RJ, Schoofs L. (2009) Evolutionary conservation of the cholecystokinin/gastrin signaling system in nematodes. Ann N Y Acad Sci., 1163:428-32.
  • De Loof A, Vandersmissen T, Huybrechts J, Landuyt B, Baggerman G, Clynen E, Lindemans M, Husson SJ, Schoofs L. (2009) APRP, the second peptide encoded by the adipokinetic hormone gene(s), is highly conserved in evolution: a role in control of ecdysteroidogenesis? Ann N Y Acad Sci., 1163:376-8.
  • Clynen E, Husson SJ, Schoofs L. (2009) Identification of new members of the (short) neuropeptide F family in locusts and Caenorhabditis elegans. Ann N Y Acad Sci., 1163:60-74.
  • Husson SJ, Lindemans M, Janssen T, Schoofs L. (2009) Comparison of Caenorhabditis elegans NLP peptides with arthropod neuropeptides. Trends Parasitol. 2009 Apr;25(4):171-81. Review
  • Boonen K, Creemers JW, Schoofs L. (2009) Bioactive peptides, networks and systems biology. Bioessays., 31(3):300-14. Review.
  • Lindemans M, Liu F, Janssen T, Husson SJ, Mertens I, Gäde G, Schoofs L. (2009) Adipokinetic hormone signaling through the gonadotropin-releasing hormone receptor modulates egg-laying in Caenorhabditis elegans. Proc Natl Acad Sci U S A., 106(5):1642-7.
  • Clynen E, Schoofs L. (2009) Peptidomic survey of the locust neuroendocrine system. Insect Biochem Mol Biol., 39(8):491-507.
  • Menschaert G, Vandekerckhove TT, Landuyt B, Hayakawa E, Schoofs L, Luyten W, Van Criekinge W. (2009) Spectral clustering in peptidomics studies helps to unravel modification profile of biologically active peptides and enhances peptide identification rate. Proteomics, 9(18):4381-8.

2008

  • Lindemans M, Janssen T, Husson SJ, Meelkop E, Temmerman L, Clynen E, Mertens I, Schoofs L. (2008) A neuromedin-pyrokinin-like neuropeptide signaling system in Caenorhabditis elegans. Biochem Biophys Res Commun., 379(3):760-4.
  • The Honey Bee Genome Sequencing Consortium (P. Verleyen) (2008). The genome of the model beetle and pest Tribolium castaneum. Nature 452: 949-955.
  • Verleyen P, Chen X, Baron S, Preumont A, Hua YJ, Schoofs L, Clynen E. (2008) Cloning of neuropeptide-like precursor 1 in the gray flesh fly and peptide identification and expression. Peptides. 2008 Dec 11. [Epub ahead of print]
  • Verleyen P, Huybrechts J, Schoofs L. (2008) SIFamide illustrates the rapid evolution in Arthropod neuropeptide research. Gen Comp Endocrinol. 2008 Oct 26. [Epub ahead of print]
  • Husson SJ, Landuyt B, Nys T, Baggerman G, Boonen K, Clynen E, Lindemans M, Janssen T & L. Schoofs (2008) Comparative peptidomics of Caenorhabditis elegans versus C. briggsae by LC-MALDI-TOF MS. Peptides. [Epub ahead of print]
  • Liu F, Baggerman G, Schoofs L & G. Wets (2008) The Construction of a Bioactive Peptide Database in Metazoa. J Proteome Res., 7(9):4119-4131.
  • Abdel-Mottaleb Y, Vandendriessche T, Clynen E, Landuyt B, Jalali A, Vatanpour H, Schoofs L & J. Tytgat (2008) OdK2, a Kv1.3 channel-selective toxin from the venom of the Iranian scorpion Odonthobuthus doriae. Toxicon, 51(8):1424-30.
  • Vanden Broeck J, Schoofs L & A. De Loof (2008) Insect neuropeptides and their receptors new leads for medical and agricultural applications. Trends Endocrinol Metab., 8(8):321-6.
  • Janssen T, Husson SJ, Lindemans M, Mertens I, Rademakers S, Ver Donck K, Geysen J, Jansen G & L. Schoofs (2008) Functional characterization of three G protein-coupled receptors for pigment dispersing factors in Caenorhabditis elegans. J Biol Chem., 283(22):15241-9.
  • Janssen T, Meelkop E, Lindemans M, Verstraelen K, Husson SJ, Temmerman L, Nachman RJ & L. Schoofs (2008) Discovery of a cholecystokinin-gastrin-like signaling system in nematodes. Endocrinology, 149(6):2826-39.
  • Boonen K, Landuyt B, Baggerman G, Husson SJ, Huybrechts J & L. Schoofs (2008) Peptidomics: the integrated approach of MS, hyphenated techniques and bioinformatics for neuropeptide analysis. J Sep Sci., 31(3):427-45.

2007

  • Saideman, S.R., M. Ma, K.K. Kutz-Naber, A. Cook, P. Torfs, L. Schoofs, L. Li & M.P. Nusbaum (2007). Modulation of rhythmic motor activity by pyrokinin peptides. J. Neurophysiol., 97(1): 579-595.
  • Sas, F., M. Begum, T. Vandersmissen, M. Geens, I. Claeys, S. Van Soest, J. Huybrechts, R. Huybrechts & A. De Loof (2007). Development of a real-time PCR assay for measurement of yellow protein mRNA transcription in the desert locust Schistocerca gregaria: A basis for isolation of a peptidergic regulatory factor. Peptides 28(1): 38-43.
  • Li B, Predel R, Neupert S, Hauser F, Tanaka Y, Cazzamali G, Williamson M, Arakane Y, Verleyen P, Schoofs L, Schachtner J, Grimmelikhuijzen CJ & Y. Park (2007) Genomics, transcriptomics, and peptidomics of neuropeptides and protein hormones in the red flour beetle Tribolium castaneum. Genome Res., 18(1):113-22.
  • Husson SJ & L. Schoofs (2007) Processing of neuropeptide precursors in Caenorhabditis elegans. Commun Agric Appl Biol Sci., 72(1):199-203.
  • Plaza L, Duvetter T, Monfort S, Clynen E, Schoofs L, Van Loey AM & ME. Hendrickx (2007) Purification and thermal and high-pressure inactivation of pectinmethylesterase isoenzymes from tomatoes (Lycopersicon esculentum): a novel pressure labile isoenzyme. J Agric Food Chem., 31;55(22):9259-65.
  • D'Hertog W, Overbergh L, Lage K, Ferreira GB, Maris M, Gysemans C, Flamez D, Cardozo AK, Van den Bergh G, Schoofs L, Arckens L, Moreau Y, Hansen DA, Eizirik DL, Waelkens E & C. Mathieu (2007) Proteomics analysis of cytokine-induced dysfunction and death in insulin-producing INS-1E cells: new insights into the pathways involved. Mol Cell Proteomics, 6(12):2180-99.
  • Husson SJ & L. Schoofs (2007) Altered neuropeptide profile of Caenorhabditis elegans lacking the chaperone protein 7B2 as analyzed by mass spectrometry. FEBS Lett., 581(22):4288-92.
  • Reumer A, Van Loy T, Clynen E & L. Schoofs (2007) How functional genomics and genetics complements insect endocrinology. Gen Comp Endocrinol., 155(1):22-30.
  • Mertens I, Husson SJ, Janssen T, Lindemans M & L. Schoofs (2007) PACAP and PDF signaling in the regulation of mammalian and insect circadian rhythms. Peptides, 28(9):1775-83.
  • Gutiérrez A, Nieto J, Pozo F, Stern S & L. Schoofs (2007) Effect of insulin/IGF-I like peptides on glucose metabolism in the white shrimp Penaeus vannamei. Gen Comp Endocrinol., 153(1-3):170-5.
  • Husson SJ, Janssen T, Baggerman G, Bogert B, Kahn-Kirby AH, Ashrafi K & L. Schoofs (2007) Impaired processing of FLP and NLP peptides in carboxypeptidase E (EGL-21)-deficient Caenorhabditis elegans as analyzed by mass spectrometry. J Neurochem., 102(1):246-60.
  • Boonen K, Baggerman G, D'Hertog W, Husson SJ, Overbergh L, Mathieu C & L. Schoofs (2007) Neuropeptides of the islets of Langerhans: a peptidomics study. Gen Comp Endocrinol., 152(2-3):231-41.
  • Husson SJ, Mertens I, Janssen T, Lindemans M, & L. Schoofs (2007) Neuropeptidergic signaling in the nematode Caenorhabditis elegans. Prog Neurobiol.,82(1):33-55.
  • Meylaers K, Freitak, D., Schoofs L. (2007). Immunocompetence of Galleria mellonella: Sex- and stage-specific differences and the physiological cost of mounting an immune response during metamorphosis. J. Insect Physiology, in press.

2006

  • Duvetter, T., I. Fraeye, D.N. Sila, I. Verlent, C. Smout, E. Clynen, L. Schoofs, H. Schols, M. Hendrickx & A. Van Loey (2006). Effect of temperature and high pressure on the activity and mode of action of fungal pectin methyl esterase. Biotechnology Progress 22(5): 1313-1320.
  • Grommen, S.V., S. Taniuchi, T. Janssen, L. Schoofs, S. Takahashi, S. Takeuchi, V.M. Darras & B. De Groef (2006). Molecular cloning, tissue distribution, and ontogenic thyroidal expression of the chicken thyrotropin receptor. Endocrinology 147(8): 3943-3951.
  • Lauwers, E., B. Landuyt, L. Arckens, L. Schoofs & W. Luyten (2006). Obestatin does not activate orphan G protein-coupled receptor GPR39. Biochemical and Biophysical Research Communications 351(1): 21-25.
  • Husson, S.J., E. Clynen, G. Baggerman, T. Janssen & L. Schoofs (2006). Defective processing of neuropeptide precursors in Caenorhabditis elegans lacking proprotein convertase 2 (KPC-2/EGL-3): mutant analysis by mass spectrometry. Journal of Neurochemistry 98(6): 1999-2012.
  • Husson, S.J. & L. Schoofs (2006). Characterization of a key neuropeptide processing enzyme in C. elegans by mass spectrometry. Communications in agricultural and applied biological sciences . 71(1): 171-174.
  • Hummon, A.B., T.A. Richmond, P. Verleyen, G. Baggerman, J. Huybrechts, M.A. Ewing, E. Vierstraete, S.L. Rodriguez-Zas, L. Schoofs, G.E. Robinson & J.V. Sweedler (2006). From the genome to the proteome: uncovering peptides in the Apis brain. Science 314(5799): 647-649.
  • The Honey Bee Genome Sequencing Consortium (G. Baggerman, J. Huybrechts, L. Schoofs, P. Verleyen, E. Vierstraete) (2006). Insights into social insects from the genome of the honeybee Apis mellifera. Nature 443: 931-949.
  • Liu, F., G. Baggerman, L. Schoofs & G. Wets (2006). Uncovering conserved patterns in bioactive peptides in Metazoa. Peptides 27(12): 3137-3153.
  • Abdel-Mottaleb, Y., E. Clynen, A. Jalali, F. Bosmans, H. Vatanpour, L. Schoofs & J. Tytgat (2006). The first potassium channel toxin from the venom of the Iranian scorpion Odonthobuthus doriae. FEBS Letters 580(26): 6254-6258.
  • Remijsen, Q.F., A. Fontayne, F. Verdonck, E. Clynen, L. Schoofs & J. Willems (2006). The antimicrobial peptide parabutoporin competes with p47(phox) as a PKC-substrate and inhibits NADPH oxidase in human neutrophils. FEBS Letters 580(26): 6206-6210.
  • De Loof, A., I. Claeys, G. Simonet, P. Verleyen, T. Vandersmissen, F. Sas & J. Huybrechts (2006). Molecular markers of phase transition in locusts. Insect Science 13: 3-12.
  • Vandersmissen, T., B. Hoste, G. Baggerman, J. Huybrechts, A. De Loof, P. Chaltin, P. Proost & M. Breuer (2006). Degradation profile of [His 7]-corazonin in the hemolymph of the desert locust Schistocerca gregaria. Peptides 27(3): 539-548.
  • B. Hoste, F. Sas, T. Vandersmissen, A. De Loof, M. Breuer and J. Huybrechts (2006). A miniaturized assay to quantitate effects of chemicals or physical stimuli upon locust activity. Insect Science 13, 401-407.
  • S.R. Saideman, A.E. Christie, P. Torfs, J. Huybrechts, L. Schoofs and M.P. Nusbaum (2006). Actions of kinin peptides in the stomatogastric ganglion of the crab Cancer borealis. Journal of Experimental Biology 209(18), 3664-3676.
  • E. Clynen, J. Huybrechts, P. Verleyen, A. De Loof and L. Schoofs(2006). Annotation of novel neuropeptide precursors in the migratory locust based on transcript screening of public EST database and mass spectrometry. BMC Genomics 7, 201 (15 p.).
  • P. Verleyen, G. Baggerman, W. D’Hertog, E. Vierstraete, S.J. Husson and L. Schoofs (2006). Identification of new immune induced molecules in the haemolymph of Drosophila melanogaster by 2D-nanoLC MS/MS. Journal of Insect Physiology 52(4), 379-388.
  • I. Mertens, I. Clinckspoor, T. Janssen, R. Nachman and L. Schoofs (2006). FMRFamide related peptide ligands activate the Caenorhabditis elegans orphan GPCR Y59H11AL.1. Peptides 27(6), 1291-1296.
  • D. Rodrigo, C. Cortés, E. Clynen, L. Schoofs, A. Van Loey and M. Hendrickx (2006). Thermal and high-pressure stability of purified Polygalacturonase and Pectinmethylesterase from four different tomato-processing varieties. Food Research International 39, 440-448.
  • F. Liu, G. Baggerman, W. D’Hertog, P. Verleyen, L. Schoofs and G. Wets (2006). In silico identification of secretory peptide genes in Drosophila melanogaster. Molecular and Cellular Proteomics 5, 510-522.
  • P. Verleyen, G. Baggerman, I. Mertens, T. Vandersmissen, J. Huybrechts, A. Van Lommel, A. De Loof and L. Schoofs (2006). C loning and characterisation of a third isoform of corazonin in the honeybee Apis mellifera. Peptides 27(3), 493-499.

2005

  • E. Clynen, L. Schoofs and M. Salzet(2005) A review of the most important classes of serine protease inhibitors in insects and leeches. Medical Chemistry Reviews-online 2(3), 197-206.
  • Husson, S.J., E. Clynen, G. Baggerman, A. De Loof & L. Schoofs (2005). Peptidomics of Caenorhabditis elegans: in search of neuropeptides. Communications in agricultural and applied biological sciences 70(2): 153-156.
  • G. Baggerman, E. Vierstraete, A. De Loof, and L. Schoofs (2005). Gel-based versus Gel-free Proteomics: A Review. Combinatorial Chemistry & High Throughput Screening 8, 669-677.
  • E. Vierstraete, P. Verleyen, A. De Loof and L. Schoofs (2005). Differential proteomics for studying Drosophila immunity. Annals of the New York Academy of Sciences 1040, 504-507.
  • I. Mertens, A. Vandingenen, E. Clynen, R.J. Nachman, A. De Loof and L. Schoofs (2005). Characterization of an RFamide-related peptide orphan GPCR in C. elegans. Annals of the New York Academy of Sciences 1040, 410-412.
  • G. Baggerman, F. Liu, G. Wets and L. Schoofs (2005). Bioinformatic analysis of peptide precursor proteins. Annals of the New York Academy of Sciences 1040, 59-65.
  • S.J. Husson, E. Clynen, G. Baggerman, A. De Loof and L. Schoofs (2005). Discovering neuropeptides in Caenorhabditis elegans by two-dimensional liquid chromatography and mass spectrometry. Biochemical and Biophysical Research Communications 335(1), 76-86.
  • I. Mertens, A. Vandingenen, E.C. Johnson, O.T. Shafer, W. Li, J.S. Trigg, A. De Loof, L. Schoofs and P.H. Taghert (2005). PDF receptor signaling in Drosophila contributes to both circadian and geotactic behaviors. Neuron 48(2), 213-219.
  • A. Jalali, F. Bosmans, M. Amininasab, E. Clynen, E. Cuypers, A. Zaremirakabadi, M.N. Sarbolouki, L. Schoofs, H. Vatanpour and J. Tytgat (2005). ODI, the first toxin isolated from the venom of the scorpion Odonthobuthus doriae active on voltage-gated Na + channels. FEBS Letters 579(19), 4181-4186.
  • I. Mertens, T. Meeusen, T. Janssen, R. Nachman and L. Schoofs (2005). Molecular characterization of two G protein-coupled receptor splice variants as FLP2 receptors in Caenorhabditis elegans. Biochemical and Biophysical Research Communications 330(3), 967-974.
  • G. Baggerman, K. Boonen, P. Verleyen, A. De Loof and L. Schoofs (2005). Peptidomic analysis of larval Drosophila melanogaster central nervous system by two-dimensional capillary liquid chromatography quadrupole time-of-flight mass spectrometry. Journal of Mass Spectrometry 40, 250-260.
  • J. Huybrechts, P. Verleyen and L. Schoofs(2005). Mass spectrometric analysis of head ganglia and neuroendocrine tissue of larval Galleria mellonella (Arthropoda, Insecta). Journal of Mass Spectrometry 40, 271-276.
  • J. Huybrechts, A. De Loof and L. Schoofs (2005). Melatonin-induced neuropeptide release from isolated locust corpora cardiaca. Peptides 26(1), 73-80.
  • R.J. Nachman, T. Vercammen, H. Williams, K. Kaczmarek K, Zabrocki J and L. Schoofs (2005). Aliphatic amino diacid Asu functions as an effective mimic of Tyr(SO(3)H) in sulfakinins for myotropic and food intake-inhibition activity in insects. Peptides 26(1), 115-120.
     

2004

  • I. Mertens, T. Meeusen, R.J. Nachman, T. Jansen, A. De Loof and L. Schoofs (2004). Functional characterization of the putative orphan neuropeptide G-protein coupled receptor C26F1.6 in Caenorhabditis elegans. FEBS Letters 573, 55-60.
  • I. Mertens, A. Vandingenen, T. Meeusen, A. De Loof and L. Schoofs (2004). Post-genomic characterization of G protein-coupled receptors. Pharmacogenomics 5, 657-672.
  • E. Clynen, A. De Loof and L. Schoofs (2004). New insights in the evolution of the GRF-superfamily based on sequence similarity between the locust APRPs and human GRF. General and Comparative Endocrinology 139(2), 173-8.
  • U. Homberg, C. Brandl, E. Clynen, L. Schoofs and J. Veenstra (2004). Mass-allatotropin/Lom-Ag-myotropin I immunostaining in the brain of the locust, Schistocerca gregaria. Cell and Tissue Research 318(2), 439-57.
  • E. Clynen and L. Schoofs (2004). A combination of liquid chromatography and mass spectrometry for peptidomic research. LC GC Europe 17, 522-529.
  • A. Vandingenen, I. Mertens, T. Meeusen, A. Cerstiaens, H. Jonckheere, W. Luyten and L. Schoofs (2004). FMRFamide-related peptide G-protein coupled receptors throughout the animal kingdom. Recent Research Developments in Biophysical Biochemistry 4, 117-143.
  • P. Verleyen, J. Huybrechts, F. Sas, E. Clynen, G. Baggerman, A. De Loof and L. Schoofs (2004). Neuropeptidomics of the grey flesh fly, Neobellieria bullata. Biochemical and Biophysical Research Communications 316, 763-770.
  • P. Verleyen, E. Clynen, J. Huybrechts, A. Van Lommel, L. Vanden Bosch, A. De Loof, J. Zdarek and L. Schoofs (2004). Fraenkel’s pupariation factor identified at last. Developmental Biology 273, 38-47.
  • G. Baggerman, P. Verleyen, E. Clynen, J. Huybrechts, A. De Loof and L. Schoofs (2004). “ Peptidomics”, a review. Journal of Chromatography B 803, 3-16.
  • J. Huybrechts, A. De Loof and L. Schoofs (2004). Diapausing Colorado potato beetles are devoid of short neuropeptide F I and II. Biochemical and Biophysical Research Communications 317, 909-916.
  • E. Vierstraete, P. Verleyen, F. Sas, G. Van den Bergh, A. De Loof, L. Arckens and L. Schoofs (2004). The instantly released Drosophila immune proteome is infection-specific. Biochemical and Biophysical Research Communications 317, 1052-1060.
  • P. Verleyen, J. Huybrechts, G. Baggerman, A. Van Lommel, A. De Loof and L. Schoofs (2004). SIFamide is a highly conserved neuropeptide: a comparative study in different insect species. Biochemical and Biophysical Research Communications 320, 334-341.
  • I. Huys, T. Olamendi-Portugal, B.I. Garcia-Gomez, I. Vandenberghe, J. Van Beeumen, K. Dyason, E. Clynen, S. Zhu, J. Van der Wal t, L. Possani and J. Tytgat (2004). A subfamily of acidic alpha-K + toxins. Journal of Biological Chemistry 279, 2781-2789.
  • B. De Groef, S.V. Grommen, I. Mertens, L. Schoofs, E.R. Kuhn and V.M. Darras (2004). Cloning and tissue distribution of the chicken type 2 corticotropin-releasing hormone receptor. General and Comparative Endocrinology 138, 89-95.
  • N. Macours, A. Vandingenen, C. Gielens, K. Hens, G. Baggerman, L. Schoofs and R. Huybrechts (2004). Isolation of angiotensin converting enzyme from testes of Locusta migratoria. European Journal of Entomology 100, 467-474 .
  • P. Verleyen, G. Baggerman, U. Wiehart, E. Schoeters, A. Van Lommel, A. De Loof and L. Schoofs (2004). Expression of a novel neuropeptide, NVGTLARDFQLPIPNamide, in the adult and larval brain of Drosophila.Journal of Neurochemistry 88, 311-319.
  • E. Vierstraete, P. Verleyen, G. Baggerman, W. D’Hertog, G. Van den Bergh, L. Arckens, A. De Loof and L. Schoofs(2004). A proteomic ap proach for the analysis of instantly released wound and immune proteins in Drosophila melanogaster hemolymph. Proceedings of the National Academy of Science 101, 470-475.
  • K. Meylaers, E. Clynen, D. Daloze, A. De Loof and L. Schoofs(2004). Identification of 1-lyso-phosphatidylethanolamine (C 16:1) as an antimicrobial compound in the housefly Musca domestica, using an antimicrobial bioassay. Insect Biochemistry Molecular Biology 34, 43-49.


2003

  • T. Meeusen, I. Mertens, A. De Loof and L. Schoofs (2003). G-protein coupled receptors in invertebrates – a state of the art. International Review of Cytology 230, 189-261.
  • E. Clynen, G. Baggerman, J. Huybrechts, L. Vanden Bosch, A. De Loof and L. Schoofs(2003). Peptidomics of the locust corpora allata: identification of novel pyrokinins (-FXPRLamides). Peptides 24, 1493-1500.
  • G. Baggerman, E. Clynen, J. Huybrechts, S. Clerens, A. De Loof and L. Schoofs (2003). Peptide profiling of a single Locusta migratoria corpus cardiacum by nano-LC tandem mass spectrometry. Peptides 24, 1475-1485.
  • A. Cerstiaens, J. Huybrechts, S. Kotanen, I. Lebeau, K. Meylaers, A. De Loof and L. Schoofs (2003). Neurotoxic and neurobehavioral effects of kynurenines in adult insects. Biochemical and Biophysical Research Communications 312, 1171-1177.
  • S. Kotanen, J. Huybrechts, A. Cerstiaens, K. Zoltan, D. Daloze, G. Baggerman, P. Forgo, A. De Loof and L. Schoofs(2003). Identification of tryptophan and beta-carboline as paralysins in larvae of the yellow mealworm, Tenebrio molitor. Biochemical and Biophysical Research Communications 310, 65-72.
  • E. Clynen, A. De Loof and L. Schoofs(2003). Mini-review: The use of peptidomics in endocrine research. General and Comparative Endocrinology 132, 1-9. I nvited paper.
  • M. Begum, N. Macours, L. Schoofs, M.M. Rahman, A. De Loof and R. Huybrechts (2003) . Cloning and tissue distribution of the cyclic AMP generating peptide of the grey flesh fly Neobellieria bullata (Diptera/Sarcophagidae). Belgian Journal of Zoology 133, 151-156.
  • M. M. Rahman, G. Baggerman, L. Schoofs, A. De Loof and M. Breuer (2003). Presence of His 7-corazonin in the central nervous system of a newly isolated albino strain of Schistocerca gregaria (Orthoptera: Acrididae): Mass spectrometric and immunocytochemical evidence. European Journal of Entomology 100, 455-458.
  • J. Huybrechts, M.P. Nusbaum, L. Vanden Bosch, G. Baggerman, A. De Loof and L. Schoofs (2003). Neuropeptidomic analysis of the brain and thoracic ganglion from the Jonah crab, Cancer borealis. Biochemical and Biophysical Research Communications 308, 535-544.
  • L. Schoofs and G. Baggerman(2003). Peptidomics in Drosophila melanogaster. Briefings in Functional Genomics and Proteomics 2, 114-120. Invited paper.
  • E. Clynen, J. Huybrechts, G. Baggerman, J. Van Doorn, D. Van der Horst, A. De Loof and L. Schoofs (2003). Identification of a glycogenolysis inhibiting peptide from the corpora cardiaca of locusts. Endocrinology 144, 3441-3448.
  • E. Vierstraete, A. Cerstiaens, G. Baggerman, G. Van den Bergh, A. De Loof and L. Schoofs (2003). Proteomics in Drosophila melanogaster: First 2D database of larval haemolymph proteins. Biochemical and Biophysical Research Communications 304, 831-838.
  • J. Huybrechts, E. Clynen, A. De Loof and L. Schoofs (2003). Osmotic lysis of corpora cardiaca using distilled water reveals the presence of partially processed peptides and peptide fragments. Physiological Entomology 28, 46-53.
  • E. Clynen, J. Huybrechts, A. De Loof and L. Schoofs (2003). Mass spectrometric analysis of the perisympathetic organs in locusts: identification of novel periviscerokinins. Biochemical and Biophysical Research Communications 300, 422-428.
  • R.A. Eigenheer, U.M. Wiehart, S.W. Nicholson, L. Schoofs, K.M. Schegg, J.J. Hull and D.A. Schooley (2003). Isolation, identification and localization of a second beetle antidiuretic peptide. Peptides 24, 27-34.
  • K. Meylaers, A. Cerstiaens, E. Vierstraete, G. Baggerman, C.W. Michiels, A. De Loof and L. Schoofs (2003). Antimicrobial compounds of low molecular mass are constituvely present in insects: characterization of ß-alanyl-tyrosine. Current Pharmaceutical Design 9, 159-174.


2002

  • T. Meeusen, I. Mertens, E. Clynen, R. Nichols, R. Nachman, R. Huybrechts, A. De Loof and L. Schoofs (2002). Identification in Drosophila melanogaster of the invertebrate G-protein coupled FMRFamide receptor. Proceedings National Academy of Science USA 99, 15363-15368.
  • M.M. Rahman, L. Vanden Bosch, G. Baggerman, E. Clynen, K. Hens, B. Hoste, K. Meylaers, T. Vercammen, L. Schoofs, A. De Loof and M. Breuer (2002). Search for peptidic molecular markers in hemolymph of crowd- (gregarious) and isolated-reared (solitary) desert locusts, Schistocerca gregaria. Peptides 23, 1907-1914.
  • G. Baggerman, A. Cerstiaens, A. De Loof and L. Schoofs (2002). Peptidomics of the larval Drosophila melanogaster central nervous system. Journal of Biological Chemistry 277, 40368-40374.
  • L. Moerman, S. Bosteels, W. Noppe, J. Willems, E. Clynen, L. Schoofs, K. Thevissen, J. Tytgat, J. Van Eldere, J. van der Walt and F. Verdonck (2002). Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa. European Journal of Biochemistry 269,4799-4810.
  • P. Torfs, G. Baggerman, T. Meeusen, J. Nieto, R.J. Nachman, J. Calderon, A. De Loof and L. Schoofs (2002). Isolation, identification and synthesis of a disulfated sulfakinin from the central nervous system of an arthropod, the white shrimp, Litopenaeus vannamei. Biochemical and Biophysical Research Communications 299, 312-320.
  • P. Torfs, R.J. Nachman, C. Poulos, A. De Loof and L. Schoofs (2002). Activity of crustacean myotropic neuropeptides on the oviduct and hindgut of the crayfish, Astacus leptodactylus. Invertebrate Reproduction and Development 41, 137-142.
  • G. Baggerman, A. Cerstiaens, L. Vanden Bosch, J. Huybrechts, E. Clynen, P. Verleyen, T. Vercammen, L. Schoofs, M. Begum and A. De Loof(2002). Search for candidate gonadotropins in extracts of the corpus cardiacum of the fleshfly, Neobellieria bullata.Invertebrate Reproduction and Development 41, 119-125.
  • I. Mertens, T. Meeusen, R. Huybrechts, A. De Loof and L. Schoofs (2002). Characterisation of the short neuropeptide F receptor from Drosophila melanogaster.Biochemical and Biophysical Research Communications 297, 1140-1148.
  • J. Huybrechts, E. Clynen, G. Baggerman, A. De Loof and L. Schoofs (2002). Isolation and identification of the AKH III precursor-related peptide from Locusta migratoria. Biochemical and Biophysical Research Communications 296, 1112-1116.
  • U. Wiehart, P. Torfs, A. Van Lommel, S.W. Nicholson and L. Schoofs (2002). Immunocytochemical localisation of a diuretic hormone of the beetle Tenebrio molitor, Tenmo-DH 37, in nervous system and midgut. Cell and Tissue Research 308, 421-429.
  • K. Hens, A. Vandingenen, N. Macours, G. Baggerman, A.C. Karaoglanovic, L. Schoofs, A. De Loof and R. Huybrechts (2002). A role of angiotensin converting enzyme in vitellogenesis: characterisation of four novel substrates originating from a yolk polypeptide gene product. European Journal of Biochemistry 269, 3522-3530.
  • A. Vandingenen, K. Hens, G. Baggerman, N. Macours, L. Schoofs, A. De Loof and R. Huybrechts (2002). Isolation and characterization of an angiotensin converting enzyme substrate from vitellogenic ovaries of the grey fleshfly, Neobellieria bullata. Peptides 23, 1853-1863.
  • A. Vandingenen, K. Hens, N. Macours, L. Schoofs, A. De Loof and R. Huybrechts (2002). Presence of angiotensin converting enzyme (ACE) interactive factors in ovaries of the grey fleshfly, Neobellieria bullata.Comparative Biochemistry and Physiology B 132, 27-35.
  • I. Huys, K. Dyason, E. Waelkens, F. Verdonck, J. van Zyl, J. du Plessis, G.J. Müller, J. van der Walt, E. Clynen, L. Schoofs and J. Tytgat (2002). Purification, characterisation and biosynthesis of parabutoxin 3, a component of Parabuthus transvaalicus venom. European Journal of Biochemistry 269, 1854-1865.
  • G. Baggerman, J. Huybrechts, E. Clynen, L. Harthoorn, D. Van der Horst, A. De Loof and L. Schoofs(2002). New insights in AKH precursor processing in Locusta migratoria obtained by capillary liquid chromatography – tandem mass spectrometry. Peptides 23, 635-644.
  • E. Clynen, D. Stubbe, A. De Loof and L. Schoofs (2002). Peptidedifferential display: a novel approach for phase transition in locusts. Comparative Biochemistry and PhysiologyB 132, 107-115.
  • E. Bender, A. Buist, M. Jurzak, X. Langlois, G. Baggerman, P. Verhasselt, M. Ercken, H.Q. Guo, C. Wintmolders, I. Van den Wyngaert, I. Van Oers, L. Schoofs and W. Luyten (2002). Adenine revealed as a signalling molecule that activates the orphan G-protein couples receptor localized on dorsal root ganglia. Proceedings National Academy of Sciences USA 99, 8573-8578.
  • L. Schoofs , E. Clynen and M. Salzet (2002). Trypsin and chymotrypsin inhibitors in insects and gut leeches. Current Pharmaceutical Design 8, 483-491.